288251-68-3

Usage

Uses

Used in Medicinal Chemistry:
1-(4-fluorophenyl)pyrrole-3-carboxylic acid is used as a building block for the development of new drugs due to its unique structure and potential biological activity. The presence of the fluorophenyl group may provide specific properties and interactions with biological targets, which could be exploited in the design of novel therapeutic agents.
Used in Organic Synthesis:
1-(4-fluorophenyl)pyrrole-3-carboxylic acid is used as a key intermediate in the synthesis of other organic compounds. Its versatile structure allows for further functionalization and modification, making it a valuable component in the creation of a wide range of chemical products.
Used in Research and Development:
1-(4-fluorophenyl)pyrrole-3-carboxylic acid is used as a subject of study in research and development efforts to better understand its properties, potential applications, and interactions with biological systems. This knowledge can then be applied to the design of new drugs and other chemical products with improved efficacy and selectivity.

Upstream product

• 169036-71-9 1-(4-fluorophenyl)-2-formylpyrrole 
• 81329-31-9 1-(4-fluorophenyl)-1H-pyrrole 
• 371-40-4 4-fluoroaniline 
• 50634-05-4 2,5-dimethoxy-3-tetrahydrofurancarboxaldehyde 
• 288251-69-4 1-(4-fluorophenyl)-3-formylpyrrole 

Downstream Products

• 288250-76-0 N-[3-cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-1-(4-fluorophenyl)pyrrole-3-carboxamide 
• 288249-80-9 N-[3-cyano-4-piperidinophenyl]-1-(4-fluorophenyl)pyrrole-3-carboxamide 
• 288249-65-0 N-[3-cyano-4-(2,2,2-trifluoroethyl)phenyl]-1-(4-fluorophenyl)pyrrole-3-carboxamide 
• 691863-34-0 5-aminomethyl-3-[1-(4-fluoro-phenyl)-1H-pyrrol-3-yl]-oxazolidin-2-one 
• 691862-98-3 3-[1-(4-fluoro-phenyl)-1H-pyrrol-3-yl]-5-hydroxymethyl-oxazolidin-2-one 
• 691862-86-9 [1-(4-fluoro-phenyl)-1H-pyrrol-3-yl]-carbamic acid benzyl ester 

Relevant academic research and scientific papers

AMIDOPYRIDINE DERIVATIVE, AND USE THEREOF

The present invention relates to novel amidopyridine derivatives. More specifically, the present invention provides a medicinal agent which is useful as a prophylactic or therapeutic agent for diseases based on the production of cytokines from T cells, comprising as the active ingredient an amidopyridine derivative or a pharmacologically acceptable salt thereof. Provided are an amidopyridine derivative of the following general formula (I): wherein each symbol has the same meaning as defined in the description, or a pharmacologically acceptable salt thereof.

Synthesis and in vitro antimycobacterial activity of novel 3-(1H-pyrrol-1-yl)-2-oxazolidinone analogues of PNU-100480

Pursuing our search program for new antitubercular drugs we decided to explore the potentiality of oxazolidinone moiety by synthesizing novel 3-(1H-pyrrol-1-yl)-2-oxazolidinone analogues of PNU-100480. The new derivatives were tested against atypical mycobacteria as well as against drug resistant Mycobacterium tuberculosis and some of them exhibited a fairly good activity against Mycobacterium avium complex (MAC).

AMIDE COMPOUNDS AND MEDICINAL USE THEREOF

The present invention relates to a compound of the formula wherein R1 is substituted aryl, heteroaryl and the like, R2 and R3 are hydrogen, alkyl, halogen, hydroxyl group and the like, Q is N, CH and the like, W is hydrogen, alkyl, hydroxycarbonylalkyl and the like, X is halogen, cyano, nitro, amino and the like, X' is hydrogen, halogen, cyano, nitro, and Y is alkyl, hydroxyl group, alkoxy, mercapto and the like and a salt thereof, and a medicine containing the said compound. The compound of the present invention shows a superior inhibitory effect on activated lymphocytes proliferation and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.