169781-83-3Relevant articles and documents
Systematic study of the luminescent europium-based nonanuclear clusters with modified 2-hydroxybenzophenone ligands
Zhang, Bin,Xiao, Ting,Liu, Chunmei,Li, Qian,Zhu, Yanyan,Tang, Mingsheng,Du, Chenxia,Song, Maoping
, p. 13332 - 13340 (2013)
The reaction of 2-hydroxybenzophenone derivatives with europium ions has afforded a new family of luminescent nonanuclear Eu(III) clusters. Crystal structure analysis of the clusters reveals that the metal core comprises two vertex-sharing square pyramida
2-(2,2-DIARYLETHYL)-CYCLIC AMINE DERIVATIVE OR SALT, SYNTHESIS THEREOF, AND APPLICATION AND COMPOSITION THEREOF
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Paragraph 0238-0239; 0296-0297, (2021/05/28)
The disclosure relates to a 2-(2,2-diarylethyl)-cyclic amine derivative or salt, a synthesis method, an application and a composition thereof. Biological activity test shows that this kind of 2-(2,2-diarylethyl)-cyclic amine derivative has good M-receptor antagonistic activity; and can be used as an active component of drugs for the treatment of the diseases mediated or regulated by muscarinic receptors, such as asthma, chronic obstructive pulmonary disease (COPD), overactive bladder (OAB), bronchospasm with chronic obstructive pulmonary disease, visceral spasm, irritable bowel syndrome, Parkinson's disease, depression or anxiety, schizophrenia and related mental diseases.
Diaryl vinyl cyclic amine derivatives and preparation method thereof
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Paragraph 0144; 0145; 0270; 0272-0275, (2018/09/08)
The invention provides diaryl vinyl cyclic amine derivatives and a preparation method thereof. The aryl substituted groups of the diaryl vinyl cyclic amine derivatives have a hydroxyl or hydroxy derivative functional groups in the ortho positions of vinyl groups. The bioactivity test shows that the compounds have anticholinergic activity, and the ortho-hydroxy groups can significantly enhance theantagonistic activity; the compounds can be used as active pharmaceutical ingredients for treating asthma, chronic obstructive pulmonary disease (COPD), rhinorrhea caused by allergic rhinitis and cold, urinary incontinence, Parkinson's disease, and the like.