170889-47-1

Upstream product

• 5111-66-0 6-Methoxy-2-naphthol 
• 7260-11-9 phenyl 2-hydroxy-3-naphthoate 
• 18515-11-2 3-methoxy-2-naphthol 
• 118495-07-1 7-(benzyloxy)-2-naphthol 
• 98793-02-3 3-benzyloxynaphthalen-2-ol 
• 135-19-3 β-naphthol 
• 2041-17-0 2-benzyloxy-6-hydroxynaphthalene 
• 5060-82-2 7-methoxy-2-naphthol 
• 1092455-29-2 3-(benzyloxy)naphthalen-2-amine 
• 2208-15-3 4-bromo-3-hydroxy-2-naphthoic acid 
• 92-70-6 3-Hydroxy-2-naphthoic acid 

Relevant academic research and scientific papers

Photochemical Oxidative Coupling of 2-Naphthols using a Hybrid Reduced Graphene Oxide/Manganese Dioxide Nanocomposite under Visible-Light Irradiation

We describe a simple, cost-effective, efficient, and high-yielding photocatalytic approach for the oxidative self-dimerization of 2-naphthols using a semiconductor–metal hybrid that consists of intercalated manganese dioxide nanoparticles in reduced graphene oxide (rGO/MnO2) under visible-light irradiation. The desired photocatalyst was synthesized in a single step by mixing MnO2 nanoparticles with rGO ultrasonically. The hybrid photocatalyst exhibited a significantly higher activity than neat MnO2 nanoparticles and rGO, which is believed to be because of the synergistic effect of its components. To our knowledge, this hybrid rGO/MnO2 nanocomposite is the first heterogeneous, green photocatalyst for the oxidative coupling of 2-naphthols under mild conditions.

Enantioselective Synthesis of 3,3′-Disubstituted 2-Amino-2′-hydroxy-1,1′-binaphthyls by Copper-Catalyzed Aerobic Oxidative Cross-Coupling

A challenging direct asymmetric catalytic aerobic oxidative cross-coupling of 2-naphthylamine and 2-naphthol, using a novel CuI/SPDO system, has been successfully developed for the first time. Enantioenriched 3,3′-disubstituted NOBINs were achieved and could be readily derived to divergent chiral ligands and catalysts. This reaction features high enantioselectivities (up to 96 % ee) and good yields (up to 80 %). The DFT calculations suggest that the F–H interactions between CF3 of L17 and H-1,8 of 2-naphthol, and the π–π stacking between the two coupling partners could play vital roles in the enantiocontrol of this cross-coupling reaction.

Nickel-Catalyzed Directed Cross-Electrophile Coupling of Phenolic Esters with Alkyl Bromides

Herein, we demonstrate the successful use of robust phenolic esters as an electrophilic acyl source in the reaction with diverse primary and secondary unactivated alkyl bromides. The cleavage of the relatively inert C-O bond is facilitated by the neighboring coordinating hydroxyl or sulfonamide moiety. By circumventing the use of pregenerated organometallics, this method allows efficient preparation of a variety of o-hydroxyl and tosyl-protected o-amino aryl ketones with high compatibility with a wide range of functionalities.

Lewis acid-assisted oxidative cross-coupling of 2-naphthol derivatives with copper catalysts

The oxidative coupling reactions between 2-naphthol and 3-hydroxy-2-naphthoic acid derivatives using a copper catalyst under an O2 atmosphere in the presence of a catalytic amount of the Lewis acid, such as Yb(OTf)3, were carried out. A highly cross-coupling selective or specific reaction effectively proceeded to give a C1 symmetrical BINOL derivative.

Highly selective oxidative cross-coupling of 2-naphthol derivatives with chiral copper(I)-bisoxazoline catalysts

The asymmetric oxidative coupling reaction of 3-hydroxy-2-naphthoate and 2-naphthol derivatives with the CuCl-(S)-(-)-2,2′-isopropylidenebis(4- phenyl-2-oxazoline) catalyst under an O2 atmosphere was carried out. The reaction proceeded in a highly cross-coupling selective manner (≤99.7%) with a moderate enantioselectivity of up to 65%.

HYDROCYANATION PROCESSES AND MULTIDENTATE PHOSPHITE LIGAND AND NICKEL CATALYST COMPOSITIONS THEREFOR

A process for hydrocyanation of an aliphatic monoethylenically unsaturated compound, in which the ethylenic double bond is not conjugated to any other unsaturated group in the molecule, which process uses a catalyst composition comprising a zero-valent nickel and a multidentate phosphite ligand in the presence of a Lewis acid promoter.

Hydrocyanation processes and multidentate phosphite ligand and nickel catalyst compositions thereof

A process for hydrocyanation of an aliphatic monoethylenically unsaturated compound, in which the ethylenic double bond is not conjugated to any other unsaturated group in the molecule, which process uses a catalyst composition comprising a zero-valent nickel and a multidentate phosphite ligand in the presence of a Lewis acid promoter.