170918-42-0Relevant articles and documents
Di[(R)-2-ethylhexyl] phthalate, a bioactive metabolite first isolated from three different bacillus species, and its synthesis
Castro, Miriam,Jiménez, Jacqueline,Ortiz, Aurelio,Sansinenea, Estibaliz
, p. 90 - 95 (2020/02/04)
Di(2-ethylhexyl) phthalate (DEHP) is the most common phthalate ester, which has been used as a plasticizer for the production of numerous polymers, particularly polyvinyl chloride (PVC). Many other groups have synthesized meso-DEHP indicating interest in this molecule, but we are the first to synthesize enantiomerically pure di[(R)-2-ethylhexyl] phthalate. We report herein, for the first time, the isolation-from the cultures of Bacillus thuringiensis, B. subtilis, and B. velezensis strains-of di[(R)-2-ethylhexyl] phthalate, enantiomerically pure and in good yields: its biological activity against bacteria and fungi was probed and for the first time its synthesis was done.
Kinetic resolution of 2-oxazolidinones via catalytic, enantioselective N-acylation
Birman, Vladimir B.,Jiang, Hui,Li, Ximin,Guo, Lei,Uffman, Eric W.
, p. 6536 - 6537 (2007/10/03)
Kinetic resolution of racemic 2-oxazolidinones via catalytic, enantioselective N-acylation has been achieved for the first time and with outstanding selectivities. Copyright
Asymmetric alkylations using SuperQuat auxiliaries - An investigation into the synthesis and stability of enolates derived from 5,5-disubstituted oxazolidin-2-ones
Bull, Steven D.,Davies, Stephen G.,Jones, Simon,Sanganee, Hitesh J.
, p. 387 - 398 (2007/10/03)
Studies on the alkylation of enolates derived from a range of N-acyl-5,5-dimethyloxazolidin-2-ones and N-acyl-5,5-diphenyloxazolidin-2-ones reveal that high yields and high diastereoselectivities are best obtained when homochiral 4-isopropyl-5,5-dimethyloxazolidin-2-one is employed as a chiral auxiliary.