171287-52-8Relevant academic research and scientific papers
Total synthesis of a mycobactin S, a siderophore and growth promoter of Mycobacterium Smegmatis, and determination of its growth inhibitory activity against Mycobacterium tuberculosis
Hu, Jingdan,Miller, Marvin J.
, p. 3462 - 3468 (1997)
A general total synthesis of mycobactins, represented by a mycobactin S, was achieved by a convergent approach. Two hydroxamic acid residues, 28 and 40b, were prepared from commercially available N(α)-Cbz-L-lysine via dimethyldioxirane oxidations. Cycliza
An Efficient Synthesis of Cobactin T, a Key Component of the Mycobactin Class of Siderophores
Hu, Jingdan,Miller, Marvin J.
, p. 6379 - 6382 (2007/10/02)
Nα-Cbz-L-lysine t-butyl ester was oxidized by dimethyldioxirane to give nitrone 8c, which was converted to azopine derivative 15.Subsequent coupling and deprotection reactions afforded an efficient synthesis of cobactin T (19).
