172688-07-2

Basic information

• Product Name: (2-oxo-5-phenyl-1,3-dioxol-4-yl)methylformate
• Synonyms: (2-oxo-5-phenyl-1,3-dioxol-4-yl)methylformate
• CAS NO: 172688-07-2
• Molecular Weight: 220.182
• Mol File: 172688-07-2.mol

Chemical Properties

• CAS DataBase Reference: (2-oxo-5-phenyl-1,3-dioxol-4-yl)methylformate(CAS DataBase Reference)
• NIST Chemistry Reference: (2-oxo-5-phenyl-1,3-dioxol-4-yl)methylformate(172688-07-2)
• EPA Substance Registry System: (2-oxo-5-phenyl-1,3-dioxol-4-yl)methylformate(172688-07-2)

Safety Data

• Hazardous Substances Data: 172688-07-2(Hazardous Substances Data)

Upstream product

• 64-18-6 formic acid 
• 80715-20-4 4-bromomethyl-1,3-dioxa-5-phenyl-cyclopenten-2-one 

Downstream Products

• 173604-88-1 (5-phenyl-2-oxo-1,3-dioxol-4-en-4-yl)methyl p-nitrophenyl carbonate 
• 173604-85-8 4-(hydroxymethyl)-5-phenyl-1,3-dioxol-4-en-2-one 

Relevant articles and documents

A convenient method for the conversion of halides to alcohols

The displacement of halides in unactivated primary bromides and iodides, allylic and benzylic primary and secondary bromides, and primary and secondary α-bromoketones by formate, using triethylammonium formate as the formylating agent, followed by acid or base catalyzed hydrolysis has been found to be an efficient method for the conversion of halides to alcohols.

N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE

The present invention provides a compound of formula (I): wherein R1a is optionally substituted C1-6 alkyl, etc.; R1m is hydrogen atom, etc.; G1, G2, G3 and G4 are (i), etc. ((i) G1 is -N(R1b)-, G2 is -CO-, G3 is -C(R1c)(R1d)-, and G4 is oxygen, etc.); R1b is optionally substituted C1-6 alkyl, etc.; R1c and R1d are each independently optionally substituted C1-6 alkyl, etc.; R2 is optionally substituted C1-6 alkyl, etc.; R3a, R3b, R3c, and R3d are each independently a group: -A-B (A is a single bond, etc., B is hydrogen atom, etc.), etc.; n is 1, etc.; R5 is C1-4 alkoxycarbonyl, etc., or a pharmaceutically acceptable salt thereof, which is useful as a renin inhibitor.

Investigation of (oxodioxolenyl)methyl carbamates as nonchiral bioreversible prodrug moieties for chiral amines

The preparation of(oxodioxolenyl)methyl carbamates and their evaluation as novel nonchiral prodrug moieties for chiral primary and secondary amino functional drugs are described. 4-(Carbamoylmethyl)-2-oxo-1,3-dioxolene derivatives of 3,4-dimethoxyphenethy