173604-88-1Relevant academic research and scientific papers
N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE
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Page/Page column 158, (2012/05/20)
The present invention provides a compound of formula (I): wherein R1a is optionally substituted C1-6 alkyl, etc.; R1m is hydrogen atom, etc.; G1, G2, G3 and G4 are (i), etc. ((i) G1 is -N(R1b)-, G2 is -CO-, G3 is -C(R1c)(R1d)-, and G4 is oxygen, etc.); R1b is optionally substituted C1-6 alkyl, etc.; R1c and R1d are each independently optionally substituted C1-6 alkyl, etc.; R2 is optionally substituted C1-6 alkyl, etc.; R3a, R3b, R3c, and R3d are each independently a group: -A-B (A is a single bond, etc., B is hydrogen atom, etc.), etc.; n is 1, etc.; R5 is C1-4 alkoxycarbonyl, etc., or a pharmaceutically acceptable salt thereof, which is useful as a renin inhibitor.
9-Aminocarbonylsubstituted derivatives of glycylcyclines
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Page/Page column 47, (2010/11/26)
This invention provides compounds of Formula I having the structure where R1, R2, R3 and A are defined in the specification or a pharmaceutically acceptable salt thereof useful as antibacterial agents. Compounds according
Investigation of (oxodioxolenyl)methyl carbamates as nonchiral bioreversible prodrug moieties for chiral amines
Alexander, Jose,Bindra, Dilbir S.,Glass, Joan D.,Holahan, Marie A.,Renyer, Mara L.,Rork, Gerald S.,Sitko, Gary R.,Stranieri, Maria T.,Stupienski, Raymond F.,Veerapanane, Hemalata,Cook, Jacquelynn J.
, p. 480 - 486 (2007/10/03)
The preparation of(oxodioxolenyl)methyl carbamates and their evaluation as novel nonchiral prodrug moieties for chiral primary and secondary amino functional drugs are described. 4-(Carbamoylmethyl)-2-oxo-1,3-dioxolene derivatives of 3,4-dimethoxyphenethy
