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17279-56-0

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17279-56-0 Usage

General Description

(2-AMINO-4-PHENYL-THIAZOL-5-YL)-PHENYL-METHANONE is a chemical compound with an intricate molecular structure. It contains a thiazole ring with a phenyl and amino group attached, as well as a phenyl-methanone functional group. (2-AMINO-4-PHENYL-THIAZOL-5-YL)-PHENYL-METHANONE has potential applications in medicinal chemistry and drug development due to its unique structure and potential pharmacological properties. Further research on the synthesis and biological activities of (2-AMINO-4-PHENYL-THIAZOL-5-YL)-PHENYL-METHANONE could provide valuable insights for the development of new pharmaceutical compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 17279-56-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,2,7 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 17279-56:
(7*1)+(6*7)+(5*2)+(4*7)+(3*9)+(2*5)+(1*6)=130
130 % 10 = 0
So 17279-56-0 is a valid CAS Registry Number.
InChI:InChI=1/C16H12N2OS/c17-16-18-13(11-7-3-1-4-8-11)15(20-16)14(19)12-9-5-2-6-10-12/h1-10H,(H2,17,18)

17279-56-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (2-Amino-4-phenylthiazol-5-yl)(phenyl)methanone

1.2 Other means of identification

Product number -
Other names (2-amino-4-phenyl-1,3-thiazol-5-yl)-phenylmethanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17279-56-0 SDS

17279-56-0Relevant articles and documents

Solvent-Controlled Synthesis of Thiocyanated Enaminones and 2-Aminothiazoles from Enaminones, KSCN, and NBS

Chen, Xue,Cuan, Xiaodan,Duan, Xiyan,Li, Huimin,Liu, Kun,Liu, Xiaojing,Wang, Junqin,Wang, Lin,Zhou, Huiyun

, (2019/10/11)

An effective and simple solvent-controlled synthesis of thiocyanated enaminones and 2-aminothiazoles has been demonstrated from enaminones, potassium thiocyanate, and N-bromosuccinimide. This process features mild reaction conditions, simple and easy oper

TBHP/AIBN-Mediated Synthesis of 2-Amino-thioazoles from Active Methylene Ketones and Thiourea under Metal-free Conditions

Sun, Jiyun,Ge, Huaibin,Zhen, Xiaohua,An, Xuechan,Zhang, Guangtao,Zhang-Negrerie, Daisy,Du, Yunfei,Zhao, Kang

, p. 2107 - 2114 (2018/03/26)

A new oxidative system of tert-butyl hydroperoxide (TBHP)/azodiisobutyronitrile (AIBN) has been used for the first time for a convenient, metal-free synthesis of substituted 2-aminothioazoles from active methylene ketone derivatives and thiourea. The reaction is postulated to proceed via an oxidative cyclization initiated by a radical process and followed by a condensation reaction.

Discovery of novel N-(5-(arylcarbonyl)thiazol-2-yl)amides and N-(5-(arylcarbonyl)thiophen-2-yl)amides as potent RORγt inhibitors

Wang, Yonghui,Cai, Wei,Zhang, Guifeng,Yang, Ting,Liu, Qian,Cheng, Yaobang,Zhou, Ling,Ma, Yingli,Cheng, Ziqiang,Lu, Sijie,Zhao, Yong-Gang,Zhang, Wei,Xiang, Zhijun,Wang, Shuai,Yang, Liuqing,Wu, Qianqian,Orband-Miller, Lisa A.,Xu, Yan,Zhang, Jing,Gao, Ruina,Huxdorf, Melanie,Xiang, Jia-Ning,Zhong, Zhong,Elliott, John D.,Leung, Stewart,Lin, Xichen

supporting information, p. 692 - 702 (2014/01/23)

Novel series of N-(5-(arylcarbonyl)thiazol-2-yl)amides and N-(5-(arylcarbonyl)thiophen-2-yl)amides were discovered as potent retinoic acid receptor-related orphan receptor-gamma-t (RORγt) inhibitors. SAR studies of the RORγt HTS hit 6a led to identification of thiazole ketone amide 8h and thiophene ketone amide 9g with high binding affinity and inhibitory activity of Th17 cell differentiation. Compound 8h showed in vivo efficacy in both mouse experimental autoimmune encephalomyelitis (EAE) and collagen induced arthritis (CIA) models via oral administration.

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