17298-18-9Relevant academic research and scientific papers
The Conversion of 5,6-Dihydro-4-methoxy-2-pyrones into 3-Alkyl-5-hydroxypyrazoles
Ayoub, Mikdad T.,Shandala, Mowafak Y.,Bashi, Galia M. Gussba,Pelter, Andrew
, p. 697 - 699 (1981)
The production and characterisation of 3--5-hydroxy-1H-pyrazoles (2a-d) and 3--5-hydroxy-1H-pyrazole (2e) by the reaction of hydrazine with 6-substituted-5,6-dihydro-4-methoxy-2-pyrones is describ
Synthesis and application of azolium ionic liquid tagged TADDOL catalysts
Yacob, Zekarias,Liebscher, Juergen
, p. 312 - 319 (2013/09/24)
Ionic liquid (IL) tagged organocatalysts based on TADDOL (α, α, α′, α′-tetraaryl-2,2-dimethyl-1,3-dioxolane-4,5- dimethanol) comprising various aryl substituents tethered with triazolium and imidazolium based ionic liquids are synthesised in good yields.
Synthesis of β-methoxyacrylate natural products based on box-Pd IIcatalyzed intermolecular methoxycarbonylation of alkynoles
Motodate, Satoshi,Kobayashi, Takuya,Fujii, Mikio,Mochida, Tomoyuki,Kusakabe, Taichi,Katoh, Shigeki,Akita, Hiroyuki,Kato, Keisuke
experimental part, p. 2221 - 2230 (2011/06/21)
Bis(oxazoline)-palladium(II) catalyzed carbonylation of homopropargyl alcohols afforded acyclic methoxyacrylate 2 and 6-membered lactone 3a-k in good combined yield. In the case of propargyl alcohols, 5-membered lactones 3p, 3q, 16 were obtained in moderate yields. The one-pot synthesis of kawa lactones 3a, 3r, 3s and formal synthesis of dihydroxycystothiazole A and dihydroxycystothiazole C are presented. To elucidate the stereochemistry of (+)-annularin G and (-)-annularin H, the first asymmetric syntheses of these natural products were achieved.
Efficient enantioselective hetero-diels-alder reaction of brassard's diene with aliphatic aldehydes: A one-step synthesis of (R)-(+)-kavain and (S)-(+)-dihydrokavain
Lin, Lili,Chen, Zhenling,Yang, Xu,Liu, Xiaohua,Feng, Xiaoming
supporting information; scheme or table, p. 1311 - 1314 (2009/04/06)
An efficient catalytic asymmetric hetero-Diels-Alder reaction of Brassard's diene with aliphatic aldehydes was reported The catalyst which was generated from (R)-BINOL, Ti(i-PrO)4, and 4-picolyl chloride hydrochloride, promoted the reaction smoothly to afford the corresponding α, β-unsaturated λ-lactone derivatives in moderate-to-good yields (46-79%) with high enantioselectivities (up to 88% ee) Natural products (R)-(+)-kavain (70% ee, > 99% ee after single re crystallization) and (S)-(+)-dihydrokavain (84% ee) were also prepared in one step by using this methodology.
Polymer-supported electron-rich diene for hetero Diels-Alder reactions
Pierres, Camille,George, Pascal,Van Hijfte, Luc,Ducep, Jean-Bernard,Hibert, Marcel,Mann, André
, p. 3645 - 3647 (2007/10/03)
A Brassard diene analogue was grafted on a modified Merrifield resin and used in a hetero Diels-Alder reaction with various aldehydes or ketones. The reaction gave access to 6-substituted 5,6-dihydropyrones (5a-u). This new immobilized electron-rich diene is more stable than the corresponding native diene, and is a versatile supported reagent.
Synthesis of 3- and 5-alkyl-6-alkyl(aryl)tetrahydropyran-2,4-diones by the condensation of β-oxo acid esters with aldehydes and ketones
Lokot',Pashkovskii,Lakhvich
, p. 707 - 714 (2007/10/03)
A method is proposed for obtaining 3- and 5-alkyl-6-alkyl(aryl)tetrahydropyran-2,4-diones based on the condensation of the dianion of alkyl(dialkyl)acetoacetic ester with aldehydes and ketones.
TIN ANALOGS OF THE VINYLOGOUS REFORMATSKY REACTION. REGIO- AND STEREOCHEMICAL CONSIDERATIONS
Fan, RuLin,Hudlicky, Tomas
, p. 5533 - 5536 (2007/10/02)
Ethyl-4-(tri-n-butyltin)-3-methyl crotonate and ethyl-4-(tri-n-butyltin)-3-methoxycrotonate were condensed with benzaldehyde and cyclohexanone.The regio- and stereochemical profiles were determined in an effort to control the course of dienolate additions
