17308-02-0Relevant articles and documents
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Salamon,Reichstein
, p. 1616,1629 (1947)
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Preparation process of 17a-hydroxyprogesterone acetate
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Paragraph 0031-0038; 0039-0046; 0047-0054, (2017/07/21)
The invention discloses a preparation process of 17a-hydroxyprogesterone acetate. According to the invention, high-purity 17a-hydroxyprogesterone acetate is obtained sequentially through an acylation reaction, a hydrolysis reaction, a neutralization reaction, centrifugation and refining. Therefore, a process procedure is shortened, raw material input is reduced, and cost is saved.
Further syntheses of cyproterone acetate
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Page/Page column 16; 28; 30; 32, (2010/02/07)
The present invention relates to improved methods for synthesising cyproterone acetate (17α-Acetoxy-6-chloro-1α, 2α-methylene-4,6-pregnadiene-3,20-dione) from solasodine. The methods of the invention are shorter as those of the prior art and therefore more economic.
Anti-glaucomatous pharmaceutical composition and the process for obtaining them
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, (2008/06/13)
The invention relates to the domain of medicinal chemistry. It concerns more particularly that of the preparation of pharmaceutical compositions for ocular use. A subject of the invention is pharmaceutical compositions for ocular use characterized in that they contain at least one selected compound of steroidal structure in combination with or admixed with a pharmaceutically-acceptable, inert carrier or vehicle. The compositions according to the invention are intended to the treatment of glaucoma.