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17308-02-0

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17308-02-0 Usage

General Description

3,20-Dioxopregn-4-en-17-beta-yl acetate, also known as Prednisolone Acetate, is a synthetic glucocorticoid drug. It is used mainly in the treatment of a wide range of inflammatory and autoimmune conditions such as asthma, uveitis, pyoderma gangrenosum, rheumatoid arthritis, ulcerative colitis, temporal arteritis and Crohn's disease, Bell's palsy, multiple sclerosis, cluster headaches, and autoimmune hepatitis. The compound works by modifying the body's immune response to different conditions, thereby reducing inflammation, swelling, and allergic-type reactions. Its use may be associated with side effects including mood changes, increased risk of infection, and bone thinning.

Check Digit Verification of cas no

The CAS Registry Mumber 17308-02-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,0 and 8 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 17308-02:
(7*1)+(6*7)+(5*3)+(4*0)+(3*8)+(2*0)+(1*2)=90
90 % 10 = 0
So 17308-02-0 is a valid CAS Registry Number.
InChI:InChI=1/C23H32O4/c1-14(24)23(27-15(2)25)12-9-20-18-6-5-16-13-17(26)7-10-21(16,3)19(18)8-11-22(20,23)4/h13,18-20H,5-12H2,1-4H3/t18-,19+,20+,21+,22+,23+/m1/s1

17308-02-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 17-Hydroxypregn-4-ene-3,20-dione acetate

1.2 Other means of identification

Product number -
Other names [(8R,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17308-02-0 SDS

17308-02-0Relevant articles and documents

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Salamon,Reichstein

, p. 1616,1629 (1947)

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Preparation process of 17a-hydroxyprogesterone acetate

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Paragraph 0031-0038; 0039-0046; 0047-0054, (2017/07/21)

The invention discloses a preparation process of 17a-hydroxyprogesterone acetate. According to the invention, high-purity 17a-hydroxyprogesterone acetate is obtained sequentially through an acylation reaction, a hydrolysis reaction, a neutralization reaction, centrifugation and refining. Therefore, a process procedure is shortened, raw material input is reduced, and cost is saved.

Further syntheses of cyproterone acetate

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Page/Page column 16; 28; 30; 32, (2010/02/07)

The present invention relates to improved methods for synthesising cyproterone acetate (17α-Acetoxy-6-chloro-1α, 2α-methylene-4,6-pregnadiene-3,20-dione) from solasodine. The methods of the invention are shorter as those of the prior art and therefore more economic.

Anti-glaucomatous pharmaceutical composition and the process for obtaining them

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, (2008/06/13)

The invention relates to the domain of medicinal chemistry. It concerns more particularly that of the preparation of pharmaceutical compositions for ocular use. A subject of the invention is pharmaceutical compositions for ocular use characterized in that they contain at least one selected compound of steroidal structure in combination with or admixed with a pharmaceutically-acceptable, inert carrier or vehicle. The compositions according to the invention are intended to the treatment of glaucoma.

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