17392-15-3

Basic information

• Product Name: 3(2H)-Benzofuranone, 2-hydroxy-
• Synonyms: 3(2H)-Benzofuranone, 2-hydroxy-;2-hydroxybenzofuran-3(2H)-one
• CAS NO: 17392-15-3
• Molecular Formula: C₈H₆O₃
• Molecular Weight: 150.13
• Mol File: 17392-15-3.mol
• Article Data: 4

Chemical Properties

• Melting Point: 108.5-110 °C(Solv: ethyl ether (60-29-7))
• Boiling Point: 327.8±42.0 °C(Predicted)
• Appearance: /
• Density: 1.456±0.06 g/cm3(Predicted)
• PKA: 10.38±0.20(Predicted)
• CAS DataBase Reference: 3(2H)-Benzofuranone, 2-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 3(2H)-Benzofuranone, 2-hydroxy-(17392-15-3)
• EPA Substance Registry System: 3(2H)-Benzofuranone, 2-hydroxy-(17392-15-3)

Safety Data

• Hazardous Substances Data: 17392-15-3(Hazardous Substances Data)

Upstream product

• 2491-36-3 2-(2-bromoacetyl)hydroxybenzene 
• 118-93-4 o-hydroxyacetophenone 
• 7647-01-0 hydrogenchloride 
• 60-29-7 diethyl ether 
• 13312-85-1 2-hydroxy-2-(2-hydroxyphenyl)acetonitrile 
• 271-89-6 1-benzofurane 
• 90-02-8 salicylaldehyde 

Downstream Products

• 57705-21-2 1-(2-hydroxylphenyl)-2-morpholinoethane-1,2-dione 

Relevant articles and documents

Highly efficient heterogeneous V2O5@TiO2 catalyzed the rapid transformation of boronic acids to phenols

A V2O5@TiO2 catalyzed green and efficient protocol for the hydroxylation of boronic acid into phenol has been developed utilizing environmentally benign oxidant hydrogen peroxide. A wide range of electron-donating and the electron-withdrawing group-containing (hetero)aryl boronic acids were transformed into their corresponding phenol. The methodology was also applied successfully to transform various natural and bioactive molecules like tocopherol, amino acids, cinchonidine, vasicinone, menthol, and pharmaceuticals such as ciprofloxacin, ibuprofen, and paracetamol. The other feature of the methodology includes gram-scale synthetic applicability, recyclability, and short reaction time.

Logical design and synthesis of indole-2,3-diones and 2-hydroxy-3(2H)- benzofuranones via one-pot intramolecular cyclization

A novel and attractive protocol to synthesis indole-2,3-diones and 2-hydroxy-3(2H)-benzofuranones and via copper(II) oxide catalyzed intramolecular cyclization is described. This method possesses functional-group compatibility, easy workup procedure, shorter reaction time and high yields.