17408-15-0

Basic information

• Product Name: 2-nitropropiophenone
• Synonyms: 2-nitropropiophenone;1-(2-nitrophenyl)propan-1-one
• CAS NO: 17408-15-0
• Molecular Formula: C₉H₉NO₃
• Molecular Weight: 179.17266
• Mol File: 17408-15-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 54-56 °C
• Boiling Point: 299.4°Cat760mmHg
• Flash Point: 140.4°C
• Appearance: /
• Density: 1.199g/cm³
• Vapor Pressure: 0.00119mmHg at 25°C
• Refractive Index: 1.548
• CAS DataBase Reference: 2-nitropropiophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-nitropropiophenone(17408-15-0)
• EPA Substance Registry System: 2-nitropropiophenone(17408-15-0)

Safety Data

• Hazardous Substances Data: 17408-15-0(Hazardous Substances Data)

Usage

General Description

2-nitropropiophenone, also known as 2-nitro-1-phenylpropan-1-one or 2-nitropropiophenone, is a chemical compound with the molecular formula C9H9NO3. It is a yellow to orange crystalline solid that is used in the synthesis of various organic compounds and pharmaceuticals. 2-nitropropiophenone is a nitro compound, consisting of a nitro functional group attached to a phenyl ring and a carbonyl group. It is commonly employed as an intermediate in the production of drugs, dyes, and organic pigments, as well as in the synthesis of various organic molecules. The compound is also known for its potential as a potent irritant and sensitizer, and its safety and handling should be carefully considered.

InChI:InChI=1/C9H9NO3/c1-2-9(11)7-5-3-4-6-8(7)10(12)13/h3-6H,2H2,1H3

Upstream product

• 93-55-0 1-phenyl-propan-1-one 
• 34812-95-8 1,3-di-tert-butyl 2-methylpropanedioate 
• 610-14-0 2-nitrobenzyl chloride 
• 323579-94-8 1-(2-nitrophenyl)-2-propen-1-ol 
• 609-73-4 o-nitroiodobenzene 
• 79-03-8 propionyl chloride 
• 1439930-82-1 (E)-1-(2-nitrophenyl)propionyl O-methyl oxime 
• 75039-34-8 (E)-propiophenone O-methyl oxime 
• 93-54-9 1-Phenyl-1-propanol 
• 7664-93-9 sulfuric acid 
• 10292-65-6 2-nitrophenylcyclopropane 
• 90972-31-9 2-(1-Hydroxypropyl)nitrobenzene 
• 7137-54-4 1-nitro-2-propyl-benzene 

Downstream Products

• 1196-28-7 2'-Aminopropiophenon 
• 10352-60-0 2,3-dimethylquinolin-4-ol 
• 6943-08-4 4-hydroxy-3-methyl-2-phenylquinoline 
• 52457-99-5 1-(2-acetylaminophenyl)-1-propanone 
• 13837-11-1 N-(2-propionylphenyl)propionamide 
• 351342-74-0 N-(2-propionylphenyl)benzamide 
• 861598-90-5 butyric acid-(2-propionyl-anilide) 
• 90972-31-9 2-(1-Hydroxypropyl)nitrobenzene 
• 98-95-3 nitrobenzene 
• 6269-45-0 2-(2-nitrophenyl)benzo[d]thiazole 
• 37465-77-3 3-(2-Nitro-phenyl)-pent-1-yn-3-ol 

Relevant articles and documents

Synthesis of Indolines and Derivatives by Aza-Heck Cyclization

For the first time, an aza-Heck cyclization that allows the preparation of indoline scaffolds is described. Using N-hydroxy anilines as electrophiles, which can be easily accessed from the corresponding nitroarenes, this method provides indolines bearing pendant functionality and complex ring topologies. Synthesis of challenging indolines, such as those bearing fully substituted carbon atoms at C2, is also possible using this method.

Pentamethylcyclopentadienyl ruthenium: an efficient catalyst for the redox isomerization of functionalized allylic alcohols into carbonyl compounds

The catalytic activity of the ruthenium(II) complex [RuCp*(CH3CN)3][PF6] 1 in the transposition of allylic alcohols into carbonyl compounds, in acetonitrile, is reported. This catalyst has proven to be able to catalyze the transformation of poorly reactive and/or functionalized substrates under smooth conditions.

CONVERSION OF 2,1-BENZISOXAZOLINIUM IONS TO ANTHRANILS BY TREATMENT WITH HYDROHALIC ACIDS

2,1-Benzisoxazolinium ions, obtained from o-nitrophenylcyclopropanes, react with hydrobromic and hydrochloric acids to give halo-substituted benzoisoxazoles.