174221-32-0

Basic information

• Product Name: (R)-3-Cyclopentyl-2-hydroxy-propionic acid benzyl ester
• CAS NO: 174221-32-0
• Molecular Weight: 248.322
• Mol File: 174221-32-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3-Cyclopentyl-2-hydroxy-propionic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-Cyclopentyl-2-hydroxy-propionic acid benzyl ester(174221-32-0)
• EPA Substance Registry System: (R)-3-Cyclopentyl-2-hydroxy-propionic acid benzyl ester(174221-32-0)

Safety Data

• Hazardous Substances Data: 174221-32-0(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 

Downstream Products

• 204637-83-2 (R)-3-Benzyloxycarbonyl-3-tert-butoxycarbonyl-2-cyclopentylmethyl-4-(3,4,4-trimethyl-2,5-dioxo-imidazolidin-1-yl)-butyric acid benzyl ester 
• 204637-81-0 (R)-2-Benzyloxycarbonyl-3-cyclopentylmethyl-succinic acid 4-benzyl ester 1-tert-butyl ester 
• 174265-38-4 cipemastat 
• 204637-85-4 1-[2(R)-[1(R)-(benzyloxycarbamoyl)-2-(3,4,4-trimethyl-2,5-dioxo-1-imidazolidinyl)ethyl]-3-cyclopentylpropionyl]piperidine 

Relevant articles and documents

Design and synthesis of the cartilage protective agent (CPA, Ro32-3555)

A novel series of MMP inhibitors has been identified. The compounds are potent selective inhibitors of collagenase with good solubility and oral bioavailability. One compound, designated Ro32-3555, has been selected for development as a cartilage protective agent for use in the treatment of rheumatoid- and osteoarthritis.