174359-58-1

Basic information

• Product Name: N^α-(tert-butyloxycarbonyl)glycylglycine p-(N',N''-bis(benzyloxycarbonyl)guanidino)phenyl ester
• Synonyms: N^α-(tert-butyloxycarbonyl)glycylglycine p-(N',N''-bis(benzyloxycarbonyl)guanidino)phenyl ester
• CAS NO: 174359-58-1
• Molecular Weight: 633.658
• Mol File: 174359-58-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N^α-(tert-butyloxycarbonyl)glycylglycine p-(N',N''-bis(benzyloxycarbonyl)guanidino)phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N^α-(tert-butyloxycarbonyl)glycylglycine p-(N',N''-bis(benzyloxycarbonyl)guanidino)phenyl ester(174359-58-1)
• EPA Substance Registry System: N^α-(tert-butyloxycarbonyl)glycylglycine p-(N',N''-bis(benzyloxycarbonyl)guanidino)phenyl ester(174359-58-1)

Safety Data

• Hazardous Substances Data: 174359-58-1(Hazardous Substances Data)

Upstream product

• 174359-51-4 (2-tert-Butoxycarbonylamino-acetylamino)-acetic acid 4-benzyloxycarbonylamino-phenyl ester 
• 174359-47-8 p-tetrahydropyran-2-yloxy-N-(benzyloxycarbonyl)aminobenzene 
• 97389-23-6 4-[(2-tetrahydropyranyloxy)methyl]aniline 
• 7107-59-7 4-(N-Benzyloxycarbonylamino)phenol 
• 31972-52-8 Boc-Gly-Gly-OH 
• 20443-91-8 2-(4-nitrophenoxy)tetrahydropyran 
• 100-02-7 4-nitro-phenol 
• 152120-55-3 N,N-bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine 

Relevant articles and documents

Synthesis and properties of N(α)-(tert-butyloxycarbonyl)peptide p- guanidinophenyl esters as trypsin substrates

N(α)-(tert-Butyloxycarbonyl)peptide p-guanidinophenyl esters were synthesized by amidination of N(α)-(tert-butyloxycarbonyl)peptide p- aminophenyl esters with 1-[N,N'-bis(benzyloxycarbonyl)amidino]pyrazole, followed by deprotection by catalytic hydrogenation, in good total yields. These synthetic esters were characterized as specific substrates for trypsin, and kinetic parameters for the trypsin-catalyzed hydrolysis are presented.