174485-29-1

Upstream product

• 1197-05-3 1-(3-amino-phenyl)-propan-1-one 
• 100-39-0 benzyl bromide 
• 17408-16-1 3'-nitropropiophenone 

Downstream Products

• 174485-30-4 6-(3-Dibenzylamino-phenyl)-6-ethyl-dihydro-pyran-2,4-dione 
• 174485-31-5 6-[3-(Dibenzyl-amino)-phenyl]-5,6-dihydro-6-ethyl-4-hydroxy-3-[1-(3-nitro-phenyl)-propyl]-pyran-2-one 
• 174485-32-6 6-(3-Amino-phenyl)-3-[1-(3-amino-phenyl)-propyl]-6-ethyl-5,6-dihydro-4-hydroxy-pyran-2-one 

Relevant academic research and scientific papers

Non-peptidic HIV protease inhibitors: C2-symmetry-based design of bis- sulfonamide dihydropyrones

Potent, non-peptidic, dihydropyrone sulfonamide HIV protease inhibitors have been previously described. Crystallographic analysis of dihydropyrone sulfonamide inhibitor/HIV protease complexes suggested incorporation of a second, C2 symmetry-rel

PYRANONE COMPOUNDS USEFUL TO TREAT RETROVIRAL INFECTIONS

The present invention relates to compounds of formulae (I) and (II) which are pyran-2-ones, 5,6-dihydro-pyran-2-ones, 4-hydroxy-benzopyran-2-ones, 4-hydroxy-cycloalkyl[b]pyran-2-ones, and derivatives thereof, useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus, wherein R 10 and R 20 taken together are formulae (III) and (IV). STR1