174690-27-8

Upstream product

• 39078-09-6 Acetic acid (1S,2S,5S,6S)-6-acetoxy-2,5-dibromo-cyclohex-3-enyl ester 
• 5273-61-0 (5RS,6RS)-5,6-dibromocyclohex-2-ene-1,4-dione 
• 54308-05-3 (1α,2β,4β,5β,7β,8α)-3,6-Dioxa-9-thiatetracyclo<6.1.0.0^2,4.0^5,7>nonan 
• 80582-73-6 (1S,2R,3S,6S)-2-bromo-7-oxabicyclo[4.1.0]hept-4-en-3-ol 
• 112212-81-4 (+/-)-(1S,2R,3R,4S)-1,4-diacetoxy-2,3-dibromocyclohex-5-ene 
• 169529-92-4 (+)-(1R,2S,3S,4R)-2,3-dibromocyclohex-5-ene-1,4-diol 
• 140696-30-6 (1R,2S,3R,6R)-2-bromo-7-oxabicyclo[4.1.0]hept-4-en-3-ol 
• 170210-89-6 (+)-(1S,2R,3R,4S)-1,4-diacetoxy-2,3-dibromocyclohex-5-ene 
• 106-51-4 p-benzoquinone 
• 69945-44-4 (1RS,2SR,3RS,4RS)-2,3-dibromocyclohex-5-ene-1,4-diol 
• 39078-11-0 cis-trisoxirane 

Downstream Products

• 120494-26-0 (1RS,2RS,3RS,6RS)-3,6-diethoxycyclohex-4-ene-1,2-diol 
• 120494-28-2 (1R,2R,3R,6R)-3,6-Di-tert-butyl-cyclohex-4-ene-1,2-diol 
• 54724-82-2 (1S,2S,4S,7S)-3,8-Bis-(toluene-4-sulfonyl)-3,8-diaza-tricyclo[5.1.0.0^2,4]oct-5-ene 
• 17793-95-2 (1RS,2RS)-cyclohexa-3,5-diene-1,2-diol 
• 281206-70-0 5,6-di-O-acetyl-1,4-bis-O-(di-O-benzylphospho)-2,3-bis-O-(3-oxo-1,5-dihydro-3λ⁵-2,4,3-benzodioxaphosphepin-3-yl)-D-myo-inositol 
• 281206-69-7 5,6-di-O-acetyl-1,4-bis-O-(di-O-benzylphospho)-D-myo-inositol 
• 281206-68-6 (1R,2S,3S,4R)-2,3-di-O-acetyl-1,4-bis-O-(di-O-benzylphospho)conduritol B 
• 120494-27-1 (1RS,2RS,3RS,6RS)-3,6-di(phenylthio)cyclohex-4-ene-1,2-diol 
• 72160-94-2 Methanesulfonic acid (1R,2S,5R,6S)-2,5-bis-methanesulfonylamino-6-methanesulfonyloxy-cyclohex-3-enyl ester 
• 114310-50-8 trans-1,3;2,6-3,6-bis(dimethylamino)-1,2-diacetoxy-4-cyclohexene 
• 114310-48-4 trans-1,3;2,6-3-dimethylamino-6-methoxy-4-cyclohexene-1,2-diol 

Relevant academic research and scientific papers

The Absolute Configurations of Anti-Benzene and Anti-Naphthalene 1,2:3,4-Dioxides

Optically active anti-1,2:3,4-dioxides of benzene and naphthalene have been synthesized and their absolute configurations assigned using the exciton chirality c.d. method.

Synthesis of novel mono and bis-indole conduritol derivatives and their α/β-glycosidase inhibitory effects

Here we synthesized four novel indole conduritol derivatives 1-4 for the first time in the literature and probed their biological activities with the α and β-glucosidases. The compounds showed quite effective glucosidase inhibitory action. IC50

Synthesis of novel cyano-cyclitols and their stereoselective biotransformation catalyzed by Rhodococcus erythropolis A4

A variety of novel cyano-cyclitols possessing complex stereochemistry have been synthesized. These compounds were subjected to the biocatalyzed hydrolysis of their nitrile groups. The bacterial strain Rhodococcus erythropolis A4, expressing a nitrile hydr

A novel chemo-multienzymatic synthesis of bioactive cyclophellitol and epi-cyclophellitol in both enantiopure forms

A new route to synthesize cyclophellitol and epi-cyclophellitol from racemic starting materials in enantiopure forms has been developed. The synthesis involves a multi-enzymatic biotransformation pathway of the novel cyano-cyclitol (1R,4S,5R,6R)/(1S,4R,5S

De novo synthesis of the enantiomers Ins(1,2,3,4)P4 and Ins(1,2,3,6)P4-regiospecificity of their enzymatic dephosphorylation

The first total synthesis of Ins(1,2,3,4)P4 and Ins(1,2,3,6)P4 is presented. Starting from p-benzoquinone, we took advantage of the C2-symmetry of conduritol-B intermediates. The target compounds were dephosphorylated by s

Enantiopure arene dioxides: Chemoenzymatic synthesis and application in the production of trans-3,4-dihydrodiols

Enantiopure syn- and anti-arene dioxides are synthesised from cis-dihydrodiol metabolites; anti-benzene dioxides are reduced to enantiopure trans-3,4-dihydrodiols while synbenzene dioxides racemise thermally via 1,4-dioxocins.

Enzyme-assisted total synthesis of the optical antipodes D-myo-inositol 3,4,5-trisphosphate and D-myo-inositol 1,5,6-trisphosphate: Aspects of their structure-activity relationship to biologically active inositol phosphates

Unambiguous total syntheses of both optical antipodes of the enantiomeric pair D-myo-inositol 3,4,5-trisphosphate (Ins(3,4,5)P3) and D- myo-inositol 1,5,6-trisphosphate (Ins(1,5,6)P3) are described. The ring system characteristic of

Concerning the reaction of anti-benzene dioxide with various nucleophiles

trans-3,4:5,6-Diepoxycyclohex-1-ene (anti-benzene dioxide) (5) was brought into reaction with several S, O, and C nucleophiles. S and O nucleophiles gave the bis-adducts stemming from independent reaction of the two epoxy functions. C nucleophiles, on the

cis-/trans--Trithia- and trans--Hexathia-tris-?-homobenzenes

Starting from the cis- and trans-benzene trioxides 2/7 the cis-/trans--Trithia-tris-?-homobenzenes 1/6 and the trans-dioxathia-/oxadithia analogs 19/21 are synthesized by regioselective epoxide opening reactions with appropriate S-nucleophiles.Under the influence of heat and light cis-trisulfide 1 quickly looses sulfur and does not undergo ?2+?2+?2>cycloreversion.Attempts to build up cis--tris-?-homobenzenes from 2 by threefold six-membered ring anellation, in the special case of 1,2-benzenedithiol as 1,4-dinucleophil, led preferably to the trans--hexathia-tris-?-homobenzene 44 (X-ray analysis) manifesting effective S-neighbouring group participation. cis-Trisulfide 1 is a poor tridentate ligand: only with Ni(ClO4)2 a 2:1 complex (presumably octahedral, 48) is formed.