17475-11-5

Basic information

• Product Name: 4,4-DIMETHYL-1-PHENYL-PENT-2-YN-1-ONE
• Synonyms: 4,4-DIMETHYL-1-PHENYL-PENT-2-YN-1-ONE
• CAS NO: 17475-11-5
• Molecular Formula: C₁₃H₁₄O
• Molecular Weight: 186.24966
• Mol File: 17475-11-5.mol
• Article Data: 39

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,4-DIMETHYL-1-PHENYL-PENT-2-YN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-DIMETHYL-1-PHENYL-PENT-2-YN-1-ONE(17475-11-5)
• EPA Substance Registry System: 4,4-DIMETHYL-1-PHENYL-PENT-2-YN-1-ONE(17475-11-5)

Safety Data

• Hazardous Substances Data: 17475-11-5(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 
• 917-92-0 3,3-Dimethylbut-1-yne 
• 201230-82-2 carbon monoxide 
• 135226-09-4 1-(3,3-dimethylbut-1-yn-1-yl)-1λ³-benzo[d][1,2]iodaoxol-3(1H)-one 
• 131-62-4 1-hydroxy-1,2-benzodioxol-3-(1H)-one 
• 14630-42-3 (3,3-dimethyl-1-butynyl)trimethylsilane 
• 88-67-5 2-Iodobenzoic acid 
• 98-88-4 benzoyl chloride 
• 37952-93-5 N-benzoyl saccharin 
• 815-17-8 trimethylpyruvic acid 
• 100-52-7 benzaldehyde 
• 611-73-4 Benzoylformic acid 
• 115505-36-7 (3,3-dimethyl-1-butynyl)(phenyl)(tetrafluoroborato)-λ³-iodane 
• 98-80-6 phenylboronic acid 

Downstream Products

• 7332-96-9 1-phenyl-3,3-dimethyl-1,2-butanedione 
• 121030-02-2 1-Cyclohexyl-4,4-dimethyl-1-phenyl-pent-2-yn-1-ol 
• 121030-00-0 2,2,9,9-Tetramethyl-5,6-diphenyl-deca-3,7-diyne-5,6-diol 
• 92-51-3 cyclohexylcyclohexane 
• 17474-12-3 4,4-dimethyl-1-phenyl-pent-2-yn-1-ol 

Relevant articles and documents

Ynonylation of Acyl Radicals by Electroinduced Homolysis of 4-Acyl-1,4-dihydropyridines

Herein we report the conversion of 4-Acyl-1,4-dihydropyridines (DHPs) into ynones under electrochemical conditions. The reaction proceeds via the homolysis of acyl-DHP under electron activation. The resulting acyl radicals react with hypervalent iodine(III) reagents to form the target ynones or ynamides in acceptable yields. This mild reaction condition allows wider functionality tolerance that includes halides, carboxylates, or alkenes. The synthetic utility of this methodology is further demonstrated by the late-stage modification of complex molecules.

Sc(OTf)3-catalyzed [3 + 2]-cycloaddition of nitrones with ynones

An efficient approach to access functionalized (2,3-dihydroisoxazol-4-yl) ketones has been developed by reacting nitrones 4 with ynones 7 or terminal ynones 10 in a one-pot fashion. The reaction went through a formal Sc(OTf)3-catalyzed [3 + 2]-cycloaddition process to generate a number of functionalized (2,3-dihydroisoxazol-4-yl) ketones 11aa-11aw, 11ba-11la and 12aa-12ae in moderate to good yields. This journal is

Visible-light-mediated photocatalytic cross-coupling of acetenyl ketones with benzyl trifluoroborate

In this report, we describe a simple visible light-triggered Barbier-type reaction by employing acetenyl ketones with benzyl trifluoroborates. Through a radical-radical cross-coupling process, this photocatalytic protocol furnished a wide range of tertiary propargyl alcohols. Mechanistic investigation indicated that proton-coupled electron transfer (PCET) might be involved in the photochemical transformations.