17485-33-5

Basic information

• Product Name: 5-chloro-2-(4-chlorophenyl)benzo[d]thiazole
• Synonyms: 5-chloro-2-(4-chlorophenyl)benzo[d]thiazole
• CAS NO: 17485-33-5
• Molecular Weight: 280.177
• Mol File: 17485-33-5.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 5-chloro-2-(4-chlorophenyl)benzo[d]thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2-(4-chlorophenyl)benzo[d]thiazole(17485-33-5)
• EPA Substance Registry System: 5-chloro-2-(4-chlorophenyl)benzo[d]thiazole(17485-33-5)

Safety Data

• Hazardous Substances Data: 17485-33-5(Hazardous Substances Data)

Upstream product

• 623-03-0 4-Cyanochlorobenzene 
• 1004-00-8 4-chloro-2-aminobenzenethiol 
• 122-01-0 4-chloro-benzoyl chloride 
• 61821-46-3 4-chloro-N-methyl-N-phenylbenzothioamide 
• 1517-46-0 4-chloro-N-methyl-N-phenyl-benzamide 
• 104-88-1 4-chlorobenzaldehyde 
• 1878-66-6 4-chlorophenylacetic Acid 
• 89-61-2 2,5-dichloronitrobenzene 
• 104-86-9 4-chlorobenzylamine 
• 2050-66-0 bis(2-nitro-4-chlorophenyl)disulfide 

Relevant articles and documents

ZnO-NPs catalyzed condensation of 2-aminothiophenol and aryl/alkyl nitriles: Efficient green synthesis of 2-substituted benzothiazoles

The synthesis of 2-substituted benzothiazoles has been described using ZnO-nanoparticles as a catalyst. The condensation of 2-aminothiophenol and aryl/alkyl nitriles resulted in the formation of various 2-substituted benzothiazoles under solvent-free reaction conditions. The library of 2-substituted benzothiazoles has been synthesized in good to excellent yield. The reaction has shown a wide range of functional group compatibility for both varyingly substituted 2-aminothiophenols and nitriles. The protocol has many advantages such as faster reaction rate, mild reaction conditions, various functional group compatibility, excellent yield, solvent-free reaction conditions, easy recovery of materials, and excellent catalyst recyclability, among others. The various advantages of this protocol make it a more feasible, economical, and environmentally benign process.

Ultrasound-assisted efficient and green synthesis of 2-substituted benzothiazoles under solvent-free condition using recyclable sulfated tungstate

Sulfated tungstate catalyzed an efficient and ecofriendly protocol has been described for the synthesis of 2-substituted benzothiazoles. The corresponding benzothiazoles were obtained using a condensation reaction of 2-aminothiophenol with various aldehydes under ultrasound irradiation at room temperature. Various functional groups on the 2-aminothiophenol as well as on the aldehydes were tolerated to provide 2-substituted benzothiazoles derivatives in excellent yields. The faster reaction rate, solvent-free or mild reaction conditions, wide functional group compatibility, excellent yields, easy work-up procedure, and excellent catalyst recyclability are the advantages of this protocol. These advantages make this process more practicable, cost-effective, and environmentally benign.

Synthesis of benzothiazoles using fluorescein as an efficient photocatalyst under visible light

This work reports a novel and efficient method for the synthesis of benzothiazoles using 2-aminothiophenol derivatives in conjunction with aromatic aldehyde as starting materials via visible-light-induced condensation cyclization. Utilizing fluorescein as the photocatalyst and blue LED lamp as the light source, the reaction proceeds in the presence of a molecular oxygen atmosphere without the need for metal catalyst or an additional oxidant. Significantly, this method exhibits good tolerance in substrates, and a variety of 2-aminothiophenol derivatives and aromatic aldehyde are amenable to producing the corresponding benzothiazoles in high to excellent yields.