175911-73-6Relevant articles and documents
Simple solid-phase synthesis and biological properties of carbohydrate - Oligonucleotide conjugates modified at the 3′-terminus
Ikeda, Yutaka,Kubota, Daisuke,Nagasaki, Yukio
experimental part, p. 1685 - 1690 (2011/11/05)
A novel synthesis method for oligonucleotides possessing a functional moiety at the 3′-terminus was established based on solid-phase synthesis. In order to install the functional group at the 3′-terminus of the oligonucleotide, a solid support possessing
Mechanism and applications of lithium amide-induced asymmetric rearrangements of 4-substituted and 4,4-disubstituted cyclopentene oxides to cyclopentenols
Hodgson, David M.,Gibbs, Andrew R.,Drew, Michael G. B.
, p. 3579 - 3590 (2007/10/03)
The preparation and lithium amide-induced rearrangements of 1,2-dideuterated 4-substituted cyclopentene oxides 11 and 19 are described, providing insight into the deprotonation mechanisms operating in such systems. Highly enantioselective syntheses of 4-substituted cis-4-hydroxymethylcyclopent-2-en-1-ols 32a-c are described. Also described are asymmetric syntheses of prostaglandin precursor 40 and (+)-iridomyrmecin (48) via highly enantioselective rearrangement of the epoxide 3 and subsequent Ireland-Claisen rearrangement. The Royal Society of Chemistry 1999.
Highly enantioselective rearrangement of quaternary carbon-containing meso-epoxides to allylic alcohols
Hodgson, David M.,Gibbs, Andrew R.
, p. 407 - 408 (2007/10/03)
The asymmetric synthesis of 4-substituted cis-4-(hydroxymethyl)cyclopent-2-en-1-ols 3 (R = alkyl, benzyloxymethyl) via highly enantioselective rearrangement of 3-substituted cis-6-oxabicyclo[3.1.0]hexane-3-methanols 1 (R = alkyl, benzyloxymethyl) is described.
