176792-02-2

Upstream product

• 139962-51-9 (4R,5S)-1,5-Dimethyl-3-((E)-pent-2-enoyl)-4-phenyl-imidazolidin-2-one 
• 139962-44-0 (4S,5R)-1-((E)-Hex-2-enoyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 176791-98-3 (4R,5S,2'R,3'S)-1,5-dimethyl-3-(2'-acetamido-3'-acetoxybutyryl)-4-phenylimidazolidin-2-one 
• 176791-97-2 (4S,5R)-1-((4R,5S)-2,5-Dimethyl-4,5-dihydro-oxazole-4-carbonyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 176791-96-1 (4S,5R)-1-((2R,3S)-1-Acetyl-3-methyl-aziridine-2-carbonyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 176792-03-3 (4R,5S)-1,5-Dimethyl-4-phenyl-3-((2R,3S)-3-propyl-aziridine-2-carbonyl)-imidazolidin-2-one 
• 176791-95-0 (4R,5S)-1,5-Dimethyl-3-((2R,3S)-3-methyl-aziridine-2-carbonyl)-4-phenyl-imidazolidin-2-one 
• 176791-94-9 (4S,5R)-1-((E)-2-Bromo-but-2-enoyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 92841-65-1 (4R,5S)-1,5-dimethyl-4-phenylimidazolidin-2-one 
• 33698-85-0 (E)-pent-2-enoyl chloride 
• 182934-91-4 (4S,5R)-1-((S)-3-Benzyloxyamino-pentanoyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 

Downstream Products

• 197232-45-4 (4S,5R)-1-((2R,3S)-1-Acetyl-3-ethyl-aziridine-2-carbonyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 197232-48-7 (4S,5R)-1-((2R,3S)-1-Benzoyl-3-ethyl-aziridine-2-carbonyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 197232-55-6 (4S,5R)-1-((4R,5S)-5-Ethyl-2-phenyl-4,5-dihydro-oxazole-4-carbonyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 

Relevant academic research and scientific papers

Synthesis of enantiomerically pure aziridine-2-imides by cyclization of chiral 3-benzyloxyamino imide enolates

Aziridine-2-imides are prepared both in high yield and high diastereoselectivity from chiral 3'-benzyloxyamino imides 2, 3, and 8 by treatment with triethylamine in the presence of either TiCl4 or AlMe2Cl. 2 and 3 are easily obtained

Asymmetrische Synthese von Alkylaziridin-2-carbonsaeureestern aus chiralen 3'-Benzyloxyaminoimiden

Keywords: Aziridine, Chirale Auxiliare, Cyclisierungen, Enolate

Synthesis of enantiomerically pure trans aziridine-2-carboxylates by diastereoselective Gabriel-Cromwell reaction

Benzyl aziridine-2-carboxylates have been obtained in high yield and selectivity by conjugate addition of ammonia to α,β-unsaturated chiral imides followed by treatment with lithium benzyloxide. A ring-expansion of the aziridine to an oxazoline allowed th