139962-51-9Relevant academic research and scientific papers
Synthesis of enantiomerically pure trans aziridine-2-carboxylates by diastereoselective Gabriel-Cromwell reaction
Cardillo, Giuliana,Gentilucci, Luca,Tomasini, Claudia,Castejon-Bordas, Maria Pilar Visa
, p. 755 - 762 (2007/10/03)
Benzyl aziridine-2-carboxylates have been obtained in high yield and selectivity by conjugate addition of ammonia to α,β-unsaturated chiral imides followed by treatment with lithium benzyloxide. A ring-expansion of the aziridine to an oxazoline allowed th
Diastereoselective additions of alkyl, akenyl, aryl and allyl cuprates to unsaturated chiral imides
Melnyk,Stephan,Pourcelot,Cresson
, p. 841 - 850 (2007/10/02)
Some diastereoselective conjugate additions of cuprates to chiral unsaturated imides bearing an imidazolidinyl group (from ephedrine and urea) show an impressive stereoselectivity. The chiral (internal auxiliary dependent) group is easily broken and recyc
