176792-03-3

Basic information

• Product Name: (4R,5S)-1,5-Dimethyl-4-phenyl-3-((2R,3S)-3-propyl-aziridine-2-carbonyl)-imidazolidin-2-one
• Synonyms: (4R,5S)-1,5-Dimethyl-4-phenyl-3-((2R,3S)-3-propyl-aziridine-2-carbonyl)-imidazolidin-2-one
• CAS NO: 176792-03-3
• Molecular Weight: 301.389
• Mol File: 176792-03-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4R,5S)-1,5-Dimethyl-4-phenyl-3-((2R,3S)-3-propyl-aziridine-2-carbonyl)-imidazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S)-1,5-Dimethyl-4-phenyl-3-((2R,3S)-3-propyl-aziridine-2-carbonyl)-imidazolidin-2-one(176792-03-3)
• EPA Substance Registry System: (4R,5S)-1,5-Dimethyl-4-phenyl-3-((2R,3S)-3-propyl-aziridine-2-carbonyl)-imidazolidin-2-one(176792-03-3)

Safety Data

• Hazardous Substances Data: 176792-03-3(Hazardous Substances Data)

Upstream product

• 139962-44-0 (4S,5R)-1-((E)-Hex-2-enoyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 183074-22-8 (4S,5R)-1-((S)-3-Benzyloxyamino-hexanoyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 

Downstream Products

• 92841-65-1 (4R,5S)-1,5-dimethyl-4-phenylimidazolidin-2-one 
• 176791-98-3 (4R,5S,2'R,3'S)-1,5-dimethyl-3-(2'-acetamido-3'-acetoxybutyryl)-4-phenylimidazolidin-2-one 
• 176791-97-2 (4S,5R)-1-((4R,5S)-2,5-Dimethyl-4,5-dihydro-oxazole-4-carbonyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 176791-96-1 (4S,5R)-1-((2R,3S)-1-Acetyl-3-methyl-aziridine-2-carbonyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 176792-02-2 (4S,5R)-1-((2R,3S)-3-Ethyl-aziridine-2-carbonyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 176791-95-0 (4R,5S)-1,5-Dimethyl-3-((2R,3S)-3-methyl-aziridine-2-carbonyl)-4-phenyl-imidazolidin-2-one 
• 176791-94-9 (4S,5R)-1-((E)-2-Bromo-but-2-enoyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 139962-51-9 (4R,5S)-1,5-Dimethyl-3-((E)-pent-2-enoyl)-4-phenyl-imidazolidin-2-one 
• 128947-02-4 (4R,5S)-1,5-dimethyl-3-[(2E)-3-phenyl-2-propenoyl]-4-phenyl-2-imidazolidinone 
• 197232-56-7 (4R,5S)-1,5-Dimethyl-4-phenyl-3-((4R,5S)-2-phenyl-5-propyl-4,5-dihydro-oxazole-4-carbonyl)-imidazolidin-2-one 
• 197232-53-4 (4R,5S)-1,5-Dimethyl-3-((4R,5S)-2-methyl-5-propyl-4,5-dihydro-oxazole-4-carbonyl)-4-phenyl-imidazolidin-2-one 
• 197232-46-5 (4S,5R)-1-((2R,3S)-1-Acetyl-3-propyl-aziridine-2-carbonyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 197232-49-8 (4S,5R)-1-((2R,3S)-1-Benzoyl-3-propyl-aziridine-2-carbonyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 

Relevant articles and documents

Synthesis of enantiomerically pure aziridine-2-imides by cyclization of chiral 3-benzyloxyamino imide enolates

Aziridine-2-imides are prepared both in high yield and high diastereoselectivity from chiral 3'-benzyloxyamino imides 2, 3, and 8 by treatment with triethylamine in the presence of either TiCl4 or AlMe2Cl. 2 and 3 are easily obtained

Synthesis of enantiomerically pure trans aziridine-2-carboxylates by diastereoselective Gabriel-Cromwell reaction

Benzyl aziridine-2-carboxylates have been obtained in high yield and selectivity by conjugate addition of ammonia to α,β-unsaturated chiral imides followed by treatment with lithium benzyloxide. A ring-expansion of the aziridine to an oxazoline allowed th