177036-79-2

Basic information

• Product Name: (S)-methyl 2-(4,6-dimethoxypyrimidin-2-yloxy)-3-methoxy-3,3-diphenylpropionate
• Synonyms: (S)-methyl 2-(4,6-dimethoxypyrimidin-2-yloxy)-3-methoxy-3,3-diphenylpropionate
• CAS NO: 177036-79-2
• Molecular Weight: 424.453
• Mol File: 177036-79-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-methyl 2-(4,6-dimethoxypyrimidin-2-yloxy)-3-methoxy-3,3-diphenylpropionate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-methyl 2-(4,6-dimethoxypyrimidin-2-yloxy)-3-methoxy-3,3-diphenylpropionate(177036-79-2)
• EPA Substance Registry System: (S)-methyl 2-(4,6-dimethoxypyrimidin-2-yloxy)-3-methoxy-3,3-diphenylpropionate(177036-79-2)

Safety Data

• Hazardous Substances Data: 177036-79-2(Hazardous Substances Data)

Upstream product

• 113583-35-0 4,6-dimethoxypyrimidin-2-yl methyl sulfone 
• 177036-78-1 (S)-2-hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester 
• 119-61-9 benzophenone 
• 178306-47-3 2-hydroxy-3-methoxy-3,3-diphenylpropionicacid methyl ester 
• 178306-51-9 (S)-2-hydroxy-3-methoxy-3,3-diphenyl propionic acid 
• 178306-52-0 (S)-2-hydroxy-3-methoxy-3,3-diphenylpropionic acid 
• 1431363-04-0 methyl 3-methoxy-2-oxo-3,3-diphenylpropionate 

Downstream Products

• 171714-84-4 darusentan 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF AN ENDOTHELIN RECEPTOR ANTAGONIST

The present invention relates to a novel process for the preparation of a compound of formula (I) wherein R is a methyl or methoxy group; to certain novel intermediates prepared in such a process and their use.

IMPROVED PROCESS FOR THE PREPARATION OF ENDOTHELIN RECEPTOR ANTAGONISTS

The present invention relates to improved processes for the preparation of Endothelin receptor antagonists, their salts and intermediates.