17747-43-2

Basic information

• Product Name: 3-ACETOXYPYRIDINE
• Synonyms: 3-Pyridinol, acetate;3-Pyridinyl acetate;3-PYRIDYL ACETATE;3-ACETOXYPYRIDINE;Acetoxypyridine;3-Aceyoxy pyridine;3-ACETOXYPYRIDINE 99%;Acetic acid 3-pyridyl ester
• CAS NO: 17747-43-2
• Molecular Formula: C₇H₇NO₂
• Molecular Weight: 137.14
• EINECS: 241-742-7
• Product Categories: Pyridines, Pyrimidines, Purines and Pteredines;Heterocyclic Compounds
• Mol File: 17747-43-2.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 92 °C9 mm Hg(lit.)
• Flash Point: 213 °F
• Appearance: /
• Density: 1.141 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.125mmHg at 25°C
• Refractive Index: n20/D 1.503(lit.)
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• PKA: 3.76±0.10(Predicted)
• CAS DataBase Reference: 3-ACETOXYPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ACETOXYPYRIDINE(17747-43-2)
• EPA Substance Registry System: 3-ACETOXYPYRIDINE(17747-43-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 17747-43-2(Hazardous Substances Data)

Usage

General Description

3-Acetoxypyridine is a chemical compound with the molecular formula C7H7NO2. It is a yellow to brown liquid that is commonly used as a building block in organic synthesis. 3-Acetoxypyridine is a versatile intermediate for the preparation of pharmaceuticals, agrochemicals, and other fine chemicals. It is also used in the production of dyestuffs, antioxidants, and rubber chemicals. Additionally, it has potential applications in the field of materials science, particularly in the development of new polymers and materials with unique properties. However, 3-Acetoxypyridine is a hazardous chemical and should be handled with caution, as it can cause irritation to the skin, eyes, and respiratory system, and may have adverse effects on human health and the environment.

InChI:InChI=1/C7H7NO2/c1-6(9)10-7-3-2-4-8-5-7/h2-5H,1H3

Upstream product

• 109-00-2 3-HYDROXYPYRIDINE 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 74-86-2 acetylene 
• 350-03-8 methyl-3-pyridylketone 
• 142-08-5 2-hydroxypyridin 
• 155164-63-9 2-acetyl-4,5-dichloropyridazin-3(2H)-one 
• 56000-40-9 2,4,6-Trimethyl-benzenesulfonate3-acetoxy-1-amino-pyridinium; 
• 81211-94-1 C₉H₁₀N₂O₃ 

Downstream Products

• 1196958-43-6 (S)-1-[5-(4-bromophenyl)-1,2,4-oxadiazol-3-yl]ethanol 
• 1196958-44-7 (1R)-1-[5-(4-bromophenyl)-1,2,4-oxadiazol-3-yl]ethyl acetate 
• 2402-77-9 2,3-dichloro-pyridine 
• 105462-24-6 risedronic acid 
• 92609-05-7 (7R,8R)-7-Methyl-1-aza-tricyclo[4.4.0.0^2,8]dec-3-en-5-one 
• 26372-53-2 N-(3-Hydroxy-2-pyridyl)-acetamid-acetat 
• 15128-91-3 3-hydroxy-2,6-dinitropyridine 
• 7295-76-3 3-methoxypyridine 
• 76509-17-6 3-benzyloxypyridine 
• 105621-27-0 3-Acetoxy-4-benzyl-4H-pyridine-1-carboxylic acid 2,2,2-trichloro-ethyl ester 

Relevant articles and documents

COMPARISON OF ANALYTICAL PYROLYSIS TECHNIQUES IN THE CHARACTERIZATION OF CHITIN.

The results of various analytical pyrolysis techniques with on-line and off-line detection have been examined with respect to characteristicity and contents of information, using chitin as a model polymer. Curie-point pyrolysis-low-energy electron impact mass spectrometry (cPy-EIMS), using normal and preheated telescopic glass tube sample holders, was applied, as well as Curie-point pyrolysis-gas chromatography/mass spectrometry, with electron impact ionization and chemical ionization (cPy-GC/EIMS, cPy-GC/CIMS).

Preparation method of 2,3-dichloropyridine

The invention provides a preparation method of 2,3-dichloropyridine. The 2,3-dichloropyridine is prepared by a one-pot method, pyridine alkyl ester serves as a raw material, and synthesis is conductedby a mode of performing chlorination, performing hydrolysis and performing chlorination again; the chlorination is substitution reaction, substitution on a benzene ring is relatively easy, the alkylester group can protect the site of the first-time chlorination reaction to be at 2 position, the hydrolysis reaction is mild in condition and rapid in reaction compared with the prior art, the second-time chlorination is to substitute the hydroxyl, the reaction is easy and the reaction condition is relatively mild. The preparation method provided by the invention is simple in operation, few threewastes are generated in the production process, requirements on equipment are low and the yield is high.

Facile esterification of alcohols with 2-Acyl-4,5-dichloropyridazin-3(2 H)-ones under Friedel-Crafts conditions

This paper describes the esterification of aromatic and aliphatic alcohols by using 2-acyl-4,5-dichloropyridazin-3(2H)-ones as an acyl source under Friedel-Crafts conditions. Twelve alcohols were reacted with four 2-acyl-4,5-dichloropyridazin-3(2H)-ones in the presence of AlCl3 in tetrahydrofuran at room temperature to give the corresponding esters in moderate to excellent yields. Thus, 2-acylpyridazin-3(2H)-ones serve as good and atom-economic acyl sources for the esterification of aromatic alcohols under Friedel-Crafts conditions, representing a rapid, practical, and efficient method of esterification. Georg Thieme Verlag Stuttgart. New York.