17764-92-0

Basic information

• Product Name: 1-(4-BROMO-2-HYDROXYPHENYL)-1-PROPANONE
• Synonyms: 1-(4-BROMO-2-HYDROXYPHENYL)-1-PROPANONE;Propiophenone, 4'-bromo-2'-hydroxy-
• CAS NO: 17764-92-0
• Molecular Formula: C₉H₉BrO₂
• Molecular Weight: 229.07
• Mol File: 17764-92-0.mol

Chemical Properties

• Melting Point: 48-49°C
• Boiling Point: 301.5°Cat760mmHg
• Flash Point: 136.1°C
• Appearance: /
• Density: 1.506g/cm³
• Vapor Pressure: 0.000588mmHg at 25°C
• Refractive Index: 1.578
• CAS DataBase Reference: 1-(4-BROMO-2-HYDROXYPHENYL)-1-PROPANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-BROMO-2-HYDROXYPHENYL)-1-PROPANONE(17764-92-0)
• EPA Substance Registry System: 1-(4-BROMO-2-HYDROXYPHENYL)-1-PROPANONE(17764-92-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 17764-92-0(Hazardous Substances Data)

Usage

Uses

1-(4-Bromo-2-hydroxyphenyl)-1-propanone is a useful compound for preparation of indazoles.

Preparation

Preparation by Friedel–Crafts acylation of m-bromophenol with propionyl chloride in the presence of aluminium chloride in refluxing ethylene dichloride for 2 h (78%)Also obtained by Fries rearrangement of 3-bromophenyl propionate in the presence of aluminium chloride at 50° for 3 h (47%).

InChI:InChI=1/C9H9BrO2/c1-2-8(11)7-4-3-6(10)5-9(7)12/h3-5,12H,2H2,1H3

Upstream product

• 591-20-8 3-Bromophenol 
• 79-03-8 propionyl chloride 
• 23689-33-0 3-bromophenyl propionic acid 

Downstream Products

• 23600-63-7 1-(4-bromo-2-methoxyphenyl)propan-1-one 
• 215815-08-0 5-bromo-2-propionylphenyl methanesulfonate 
• 215815-09-1 6-bromo-1-methyl-3-ethyl-1H-indazole 
• 23600-65-9 3-Brom-6-<1-hydroxy-propyl>-anisol 
• 23600-70-6 2,3,4-Tribrom-6-<1-hydroxy-propyl>-anisol 
• 23600-68-2 2,3,4-Tribrom-6-propionyl-anisol 
• 1375999-01-1 1-(3-allyl-4-bromo-2-hydroxyphenyl)propan-1-one 
• 1375998-97-2 1-(2-allyloxy-4-bromo-phenyl)propan-1-one 
• 1607025-26-2 methyl 3-hydroxy-4-(1-iminopropyl)benzoate 
• 1607025-27-3 methyl 3-ethylbenzo[d]isoxazole-6-carboxylate 

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