177748-19-5

Basic information

• Product Name: (E)-1-[4-[2-(N,N-DIMETHYLAMINO)ETHOXY]PHENYL]-1-[4-(TRIMETHYLACETOXY)PHENYL]-2-PHENYLBUT-1-ENE
• Synonyms: (E)-1-[4-[2-(N,N-DIMETHYLAMINO)ETHOXY]PHENYL]-1-[4-(TRIMETHYLACETOXY)PHENYL]-2-PHENYLBUT-1-ENE;(E)-4-O-Butoxycarbonyl TaMoxifen
• CAS NO: 177748-19-5
• Molecular Formula: C31H37NO3
• Molecular Weight: 471.63
• Product Categories: Drug Analogues;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
• Mol File: 177748-19-5.mol
• Article Data: 2

Chemical Properties

• Melting Point: 113-115°C
• Appearance: /
• Solubility: Dichloromethane, Ethyl Acetate, Methanol
• CAS DataBase Reference: (E)-1-[4-[2-(N,N-DIMETHYLAMINO)ETHOXY]PHENYL]-1-[4-(TRIMETHYLACETOXY)PHENYL]-2-PHENYLBUT-1-ENE(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-[4-[2-(N,N-DIMETHYLAMINO)ETHOXY]PHENYL]-1-[4-(TRIMETHYLACETOXY)PHENYL]-2-PHENYLBUT-1-ENE(177748-19-5)
• EPA Substance Registry System: (E)-1-[4-[2-(N,N-DIMETHYLAMINO)ETHOXY]PHENYL]-1-[4-(TRIMETHYLACETOXY)PHENYL]-2-PHENYLBUT-1-ENE(177748-19-5)

Safety Data

• Hazardous Substances Data: 177748-19-5(Hazardous Substances Data)

Usage

Chemical Properties

Leight Beige Solid

Upstream product

• 114031-67-3 [4-(4-hydroxybenzoyl)phenyl]-2,2-dimethyl propanoate 
• 93-55-0 1-phenyl-propan-1-one 
• 3282-30-2 pivaloyl chloride 
• 68392-35-8 4-hydroxytamoxifen 
• 107-99-3 2-(dimethylamino)ethyl chloride 
• 177748-17-3 (E)-1-(4-hydroxyphenyl)-1-[4-(trimethylacetoxy)phenyl]-2-phenylbut-1-ene 

Relevant articles and documents

Clomiphene and tamoxifen analogues AS potential non-steroidal antiestrogens

The synthesis of some Clomiphene and Tamoxifen analogs is reported. These compounds were designed by choosing the matching substituents and their positions so as to improve the biological activity in the treatment of hormone-dependent tumours.