17851-47-7

Usage

Physical state

Colorless, viscous liquid

Odor

Floral, rose-like

Uses

a. Fragrance ingredient in personal care and cosmetic products
b. Solvent in pharmaceutical manufacturing
c. Potential precursor in the synthesis of organic compounds

Upstream product

• 71-43-2 benzene 
• 1501-05-9 5-oxo-5-phenylvaleric acid 
• 1501-04-8 Methyl 4-benzoylbutanoate 
• 108-55-4 glutaric anhydride, 
• 73172-56-2 ethyl 4-benzoylbutanoate 
• 17851-44-4 ethyl 6-phenyl 5,5-(ethylenedioxy)hexanoate 
• 381294-88-8 methyl 4-(2-phenyl-1,3-dioxolan-2-yl)butanoate 

Downstream Products

• 111183-78-9 1-phenylheptane-1,5-dione 
• 209725-89-3 3-hydroxy-7-ethylenedioxy-7-phenylheptane 
• 353460-45-4 ethyl (E)-7-oxo-7-phenylhept-2-enoate 
• 165613-10-5 5,5-(ethylenedioxy)-5-phenylpentanal 
• 942-93-8 5-Chloro-1-phenyl-1-pentanone 

Relevant academic research and scientific papers

Ketones as precursors of active compounds

A compound of formula wherein Y represents a pyridyl group, or a phenyl group of formula wherein R3 represents a hydrogen atom, a CF3 group or an alkoxy group, R4 represents a hydrogen atom, an alkyl group, or a CF3

The First Tandem [2 + 2] Cycloaddition-Michael Reaction Using Ynolates: Facile Construction of Substituted Carbocycles

(matrix presented) A tandem [2 + 2] cycloaddition-Michael reaction using ynolate anions followed by decarboxylation produced polysubstituted five-, six-, and seven-membered cycloalkenes.

A convenient synthesis of 1-phenyl-heptane-1,5-dione

An efficient synthesis of the title compound 9 has been developed via Friedel-Craft acylation of benzene and subsequent manipulation of the functionalities of the condensation product 3 for generation of the required 1,5-dione moiety.