178677-22-0Relevant academic research and scientific papers
Synthesis of a novel series of benzocycloalkene derivatives as melatonin receptor agonists
Fukatsu, Kohji,Uchikawa, Osamu,Kawada, Mitsuru,Yamano, Toru,Yamashita, Masayuki,Kato, Koki,Hirai, Keisuke,Hinuma, Shuji,Miyamoto, Masaomi,Ohkawa, Shigenori
, p. 4212 - 4221 (2007/10/03)
We synthesized a novel series of benzocycloalkene derivatives and evaluated their binding affinities to melatonin receptors. To control the spatial position of the amide group, one of the important pharmacophores, we incorporated an endo double bond, an e
Benzocycloalkene compounds, their production and use
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, (2008/06/13)
A compound of the formula wherein R1and R2are H, a hydrocarbon group or a heterocyclic group, or R1and R2are combinedly a spiro ring; R3is a hydrocarbon group, a substituted amino group, a substituted
Benzocycloalkene compounds, their production and use
-
, (2008/06/13)
A compound of the formula STR1 wherein R1 and R2 independently represent H or an optionally substituted hydrocarbon group; R3 represents an optionally substituted hydrocarbon group; R4 represents H or a hydrocarbon group; ring A represents a substituted benzene ring; X represents a C2-4 alkylene group etc.; and Y represents a bond or a lower alkylene group, or salts thereof is useful as prophylactic or therapeutic agents of diseases related with melatonin activity.
