17993-73-6

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 613-91-2 acetophenone oxime 
• 3385-94-2 hexamethyldisilathiane 
• 4039-32-1 lithium hexamethyldisilazane 
• 98-86-2 acetophenone 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 50314-86-8 acetophenone oxime 

Downstream Products

• 2627-86-3 (S)-1-phenyl-ethylamine 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 103-84-4 Acetanilid 
• 13599-24-1 ethyl 3-phenylisoxazole-5-carboxylate 
• 169271-95-8 ethyl 4-phenyl-4-hydroximino-2-oxobutyrate 

Relevant academic research and scientific papers

Selective silylation of alcohols, phenols and oximes using N-chlorosaccharin as an efficient catalyst under mild and solvent-free conditions

Efficient silylation of OH group in alcohols, phenols and oximes is described using a catalytic amount of N-chlorosaccharin and hexamethyldisilazane (HMDS) under mild and solvent-free conditions. This silylation reaction can be carried out with excellent and interesting various selectivities.

An efficient method for the silylation of hydroxyl groups with hexamethyldisilazane (HMDS) catalyzed by aluminum tris(dihydrogen phosphate) under solvent-free and ambient conditions

A highly efficient and mild procedure for the trimethylsilylation of a wide variety of alcohols, including primary, benzylic, secondary, hindered secondary, tertiary, phenols, and oximes with hexamethyldisilazane (HMDS), using Al(H2PO4)3 as a recyclable heterogeneous catalyst at room temperature in a few minutes with excellent yields under solvent-free conditions is described.

Alumina perchloric acid (Al2O3-HClO4) as an efficient heterogeneous catalyst for modified preparation of trimethylsilyl ethers

A highly efficient and mild procedure for the trimethylsilylation of a wide variety of alcohols, including primary, benzylic, secondary, hindered secondary, tertiary, phenols, and oximes with hexamethyldisilazane (HMDS) using alumina perchloric acid (Al2O3-HClO4) as recyclable heterogeneous catalyst in excellent yields with short reaction times (3-65 min) under ambient conditions is described. Copyright Taylor & Francis Group, LLC.

Regioisomeric 5(3)-aminomethyl-3(5)-phenylisoxazoles: Synthesis, spectroscopic discrimination, and muscarinic activity

The regioselective synthesis of isomeric 5(3)-aminomethyl-3(5)-phenyl isoxazoles using different methods is described. Spectroscopic data, especially mass spectrometric fragmentation, were used to identify and characterize the regioisomers. The muscarinic

The catalytic Friedel-Crafts acylation reaction and the catalytic Beckmann rearrangement promoted by a Gallium(III) or an antimony(V) cationic species

The catalytic Friedel-Crafts acylation reaction and the catalytic Beckmann rearrangement are successfully carried out by using the active cationic species dichlorogallium(III) perchlorate and tetrachloroantimonium(V) hexafluoroantimonate(V), respectively, which were generated in situ from appropriate silver, gallium(III) or antimony(V) salts.

A New Synthesis of Oxime Derivatives from Carbonyl Compounds and N,O-Bis(trimethylsilyl)hydroxylamine

Reaction of a series of aldehydes and ketones with the potassium salt of N,O-bis(trimethylsilyl)hydroxylamine (2) gave high yields of the corresponding oximate anion 5.This anion, formed in a Peterson-type reaction, could be protonated to the oxime 7 or trapped in situ with a variety of electrophiles to give O-substituted oxime derivatives.

Asymmetric Synthesis Using Chirally Modified Borohydrides. Part 3. Enantioselective Reduction of Ketones and Oxime Ethers with Reagents Prepared from Borane and Chiral Amino Alcohols

The asymmetric reduction of aromatic and aliphatic ketones, halogeno ketones, keto esters, and ketone oxime ethers with reagents prepared from borane and chiral amino alcohols has been investigated.When α,α-diphenyl-β-amino alcohols, such as (2S,3R)-(-)-2-amino-3-methyl-1,1-diphenylpentanol (2d), were used as a chiral auxiliary, very high enantioselectivities (ca. 90percent e.e.) were obtained in the reduction of various ketones and oxime ethers.