180322-77-4

Upstream product

• 100-42-5 styrene 
• 711011-08-4 (1R,2S)-methyl 2-phenyl-1-{1-{(triisopropylsilyl)oxy}ethenyl}cyclopropanecarboxylate 
• 153062-73-8 (1S,2S)-methyl 2β-phenyl-1β-((E)-2-phenylethenyl)cyclopropane-1α-carboxylate 
• 711011-05-1 methyl 3-(tri(isopropyl)silanyloxy)-2-diazo-but-3-enoate 

Downstream Products

• 158723-71-8 (R)-methyl 4-(3,4-dichlorophenyl)-4-phenyl-2-methoxycarbonylbutanoate 
• 180322-78-5 (1S,2S)-1-tert-Butoxycarbonylamino-2-phenyl-cyclopropanecarboxylic acid methyl ester 
• 180322-80-9 methyl (1R,2S)-1-[(tert-butoxycarbonyl)amino]-2-phenylcyclopropanecarboxylate 
• 180322-79-6 (1S,2S)-(Z)-1-[N-[[(1,1-dimethylethyl)oxy]carbonyl]amino]-2-phenylcyclopropane-1-carboxylic acid 
• 244205-60-5 (1R,2S)-1-tert-Butoxycarbonylamino-2-phenyl-cyclopropanecarboxylic acid 
• 158800-59-0 (1S,2S)-2-phenyl-1-(pyrrolidin-1-ylcarbonyl)cyclopropanecarboxylic acid 
• 123806-63-3 methyl (1R,2S)-1-amino-2-phenylcyclopropanecarboxylate 
• 86087-22-1 (+)-(2R)-Cyclopropyl-E-phenylalanine 
• 110769-86-3 (Z)-2,3-methanophenylalanine methyl ester 
• 158800-60-3 dimethyl (2S)-2-phenylcyclopropane-1,1-dicarboxylate 

Relevant academic research and scientific papers

FLUORINATION OF ORGANIC COMPOUNDS

Methods for fluorinating organic compounds are described herein.

Asymmetric cyclopropanations and cycloadditions of dioxocarbenes

Methods for enantioselective transfer of carbenes starting from precursors carrying two carbonyl groups have been elaborated. A one-pot procedure for olefin cyclopropanation with CH-acidic precursors via intermediate phenyliodonium ylides has been develop

Selectivity enhancement in the Rh(II)-catalyzed cyclopropanation of styrene with (Silanyloxyvinyl)diazoacetates

Matrix presented. The cyclopropanation of styrene with (silanyloxyvinyl) diazoacetates proceeds with exceptional diastereo- and enantioselectivity in the presence of chiral Rh(II) catalysts. 1,8-Naphthoyl-protected amino acids are the most effective Rh(II) ligands for these transformations.

Asymmetric cyclopropanations by rhodium(II) N-(arylsulfonyl)prolinate catalyzed decomposition of vinyldiazomethanes in the presence of alkenes. Practical enantioselective synthesis of the four stereoisomers of 2-phenylcyclopropan-1-amino acid

The rhodium N-(arylsulfonyl)prolinate catalyzed decomposition of vinyldiazomethanes in the presence of alkenes leads to a very general method for the synthesis of functionalized cyclopropanes in a highly diastereoselective and enantioselective mode. A det

A Catalytic Enantioselective Synthetic Route to the Important Antidepressant Sertraline

An efficient catalytic enantioselective synthesis of the important antidepressant sertraline is described.