181289-06-5

Basic information

• Product Name: 3-(4-((4-cyanophenoxy)methyl)piperidin-1-yl)propyl methanesulfonate
• Synonyms: 3-(4-((4-cyanophenoxy)methyl)piperidin-1-yl)propyl methanesulfonate
• CAS NO: 181289-06-5
• Molecular Weight: 352.455
• Mol File: 181289-06-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(4-((4-cyanophenoxy)methyl)piperidin-1-yl)propyl methanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-((4-cyanophenoxy)methyl)piperidin-1-yl)propyl methanesulfonate(181289-06-5)
• EPA Substance Registry System: 3-(4-((4-cyanophenoxy)methyl)piperidin-1-yl)propyl methanesulfonate(181289-06-5)

Safety Data

• Hazardous Substances Data: 181289-06-5(Hazardous Substances Data)

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 181289-05-4 1-[(3-hydroxypropyl)-4-(4-cyanophenoxymethyl)]piperidine 
• 176967-62-7 4-<(4-cyanophenoxy)methyl>piperidine 
• 123855-51-6 tert-butyl 4-(hydroxymethyl)piperidin-1-carboxylate 
• 767-00-0 4-cyanophenol 
• 176967-61-6 1-(tert-butoxycarbonyl)-4-(4-cyanophenoxymethyl)piperidine 
• 7143-01-3 Methanesulfonic anhydride 

Relevant articles and documents

Utility of azetidinium methanesulfonates for radiosynthesis of 3-[ 18F]fluoropropyl amines

3-Methanesulfonyloxypropyl tertiary amines were observed to cyclize to form azetidinium methanesulfonate moieties. Heat-induced cyclization of 3-methanesulfonyloxypropyl amines was utilized for preparation of azetidinium methanesulfonates. The azetidinium methanesulfonates were found to incorporate radioactive [18F]fluoride (decay-corrected yields > 60%) efficiently, resulting in an efficient synthesis of 3-[18F] fluoropropyl tertiary amines. Copyright