181717-14-6

Basic information

• Product Name: 3-(2-iodophenyl)propyl methanesulfonate
• Synonyms: 3-(2-iodophenyl)propyl methanesulfonate
• CAS NO: 181717-14-6
• Molecular Weight: 340.182
• Mol File: 181717-14-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-(2-iodophenyl)propyl methanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-iodophenyl)propyl methanesulfonate(181717-14-6)
• EPA Substance Registry System: 3-(2-iodophenyl)propyl methanesulfonate(181717-14-6)

Safety Data

• Hazardous Substances Data: 181717-14-6(Hazardous Substances Data)

Upstream product

• 26059-41-6 3-(2-iodophenyl)-1-propanol 
• 124-63-0 methanesulfonyl chloride 
• 128823-38-1 3-(2-iodophenyl)propanenitrile 
• 18698-96-9 o-iodophenylacetic acid 
• 96606-95-0 3-(2-iodophenyl)propanoic acid 
• 5159-41-1 2-iodobenzyl alcohol 
• 183789-20-0 2-iodobenzyl methanesulfonate 
• 40400-13-3 2-Iodobenzyl bromide 
• 111373-31-0 diethyl (2-iodobenzyl)malonate 
• 181717-12-4 2-(o-iodophenyl)ethyl methanesulfonate 
• 26059-40-5 2-(2-iodophenyl)ethan-1-ol 

Downstream Products

• 87562-51-4 2,2-dimethyl-5-phenylpentanenitrile 
• 495414-08-9 5-(2-iodophenyl)-2,2-dimethylpentanenitrile 
• 123387-53-1 tert-butyl 1,2,3,4-tetrahydroquinoline-1-carboxylate 
• 1429337-71-2 1-(phenyl)-6,7-dihydro-5H-benzo[c][1,2,3]triazolo[1,5-a]azepine 
• 1429337-72-3 1-(4-methoxyphenyl)-6,7-dihydro-5H-benzo[c]-[1,2,3]triazolo[1,5-a]azepine 
• 1429337-73-4 1-(4-nitrophenyl)-6,7-dihydro-5H-benzo[c][1,2,3]triazolo[1,5-a]azepine 
• 1429337-74-5 1-(2,4-dimethoxypyrimidin-5-yl)-6,7-dihydro-5H-benzo[c][1,2,3]triazolo[1,5-a]azepine 
• 1429337-75-6 1-({(3aR,5R,6S,6aR)-5-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-6-yl-oxy}methyl)-6,7-dihydro-5H-benzo[c][1,2,3]triazolo[1,5-a]azepine 
• 1429337-87-0 1-(3-azidopropyl)-2-iodobenzene 
• 1592933-53-3 3-(2-iodophenyl)propyl tert-butyl peroxide 
• 1592933-67-9 3-(2-deuterophenyl)propyl tert-butyl peroxide 
• 115860-48-5 1-iodo-3-(2-iodophenyl)propane 

Relevant articles and documents

Oxacycle synthesis via intramolecular reaction of carbanions and peroxides

The intramolecular reaction of dialkyl peroxides with carbanions, generated via chemoselective metal-heteroatom exchange or deprotonation, provides a new approach to cyclic ethers. Applied in tandem with C-C bond formation, the strategy enables a one-step annelation to form oxaospirocycles.

Synthesis of indolines via a domino Cu-catalyzed amidation/cyclization reaction

(Chemical Equation Presented) A highly efficient one-pot procedure for the synthesis of indolines and their homologues based on a domino Cu-catalyzed amidation/nucleophilic substitution reaction has been developed. Substituted 2-iodophenethyl mesylates and related compounds afforded the corresponding products in excellent yields. No erosion of optical purity was observed when transforming enantiomerically pure mesylates under the reaction conditions.

Controlled double-bond migration in palladium-catalyzed intramolecular arylation of enamidines

Palladium-catalyzed intramolecular cyclization of N-(N′-tert-butylformimidoyl)-6-[2-(2-iodophenyl)-ethyl]-1,2,3,4- tetrahydropyridine (1a) and N-(N′-tert-butylformimidoyl)-6-[3-(2-iodophenyl)propyl]-1,2,3,4- tetrahydropyridine (1b) respectively results in formation of spiro compounds 1′-(N-tert-butylformimidoyl)-3′,4′-dihydrospiro[indan-1, 2′(1′H)-pyridine] (4a), 1′-(N-tert-butylformimidoyl)-1′,6′-dihydrospiro[indan-1, 2′(3′H)-pyridine] (5a), and 1′-(N-tert-butylformimidoyl)-5′,6′-dihydrospiro[indan-1, 2′(1′H)-pyridine] (6a) and 1′-(N-tert-butylformimidoyl)-3,3′,4,4′- tetrahydrospiro[naphthalene-1(2H),2′(1′H)-pyridine] (4b), 1′-(N-tert-butylformimidoyl)-1′,3,4,6′- tetrahydrospiro[naphthalene-1(2H),2′(3′H)-pyridine] (5b), and 1′-(N-tert-butylformimidoyl)-3,4,5′,6′- tetrahydrospiro[naphthalene-1(2H),2′(1′H)-pyridine] (6b). The double-bond migration process can be controlled, and any of the three double-bond isomers can be prepared by employing proper ligands. A combination of BINAP and the amidine function was required to obtain the isomers 5a and 5b with the double bond in the homoallylic position relative to the aryl group. An electrospray ionization mass spectrometric study was conducted to support suggested reaction intermediates.