26059-41-6

Upstream product

• 40888-21-9 methyl (E)-3-(2′-iodophenyl)acrylate 
• 128823-38-1 3-(2-iodophenyl)propanenitrile 
• 18698-96-9 o-iodophenylacetic acid 
• 40400-13-3 2-Iodobenzyl bromide 
• 105-53-3 diethyl malonate 
• 533-58-4 2-Iodophenol 
• 412272-54-9 ethyl 3-(2-iodophenyl)acrylate 
• 15115-58-9 3-(2-bromophenyl)propionic acid 
• 183789-20-0 2-iodobenzyl methanesulfonate 
• 52221-92-8 3-(2-bromo-phenyl)-propan-1-ol 
• 59473-45-9 2-(chloromethyl)iodobenzene 
• 5159-41-1 2-iodobenzyl alcohol 
• 26260-02-6 2-iodobenzaldehyde 
• 111373-31-0 diethyl (2-iodobenzyl)malonate 

Downstream Products

• 181717-14-6 3-(2-iodophenyl)propyl methanesulfonate 
• 115860-48-5 1-iodo-3-(2-iodophenyl)propane 
• 87562-51-4 2,2-dimethyl-5-phenylpentanenitrile 
• 495414-08-9 5-(2-iodophenyl)-2,2-dimethylpentanenitrile 
• 188990-11-6 N-<3-(2-Iodophenyl)propyl>serine methyl ester 
• 188990-05-8 2-{tert-Butoxycarbonyl-[3-(2-iodo-phenyl)-propyl]-amino}-acrylic acid methyl ester 
• 1093413-26-3 N-benzyl-N-(o-nitrobenzenesulfonyl)-3-(o-iodophenyl)propylamine 
• 1093413-27-4 N-(tert-butoxycarbonyl)-N-(o-nitrobenzenesulfonyl)-3-(o-iodophenyl)propylamine 
• 1271193-05-5 2-(3-(2-iodophenyl)propyl)-3-oxocyclohex-1-enyl trifluoromethanesulfonate 
• 1429337-71-2 1-(phenyl)-6,7-dihydro-5H-benzo[c][1,2,3]triazolo[1,5-a]azepine 
• 1429337-72-3 1-(4-methoxyphenyl)-6,7-dihydro-5H-benzo[c]-[1,2,3]triazolo[1,5-a]azepine 
• 1429337-73-4 1-(4-nitrophenyl)-6,7-dihydro-5H-benzo[c][1,2,3]triazolo[1,5-a]azepine 
• 1429337-74-5 1-(2,4-dimethoxypyrimidin-5-yl)-6,7-dihydro-5H-benzo[c][1,2,3]triazolo[1,5-a]azepine 
• 1429337-75-6 1-({(3aR,5R,6S,6aR)-5-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-6-yl-oxy}methyl)-6,7-dihydro-5H-benzo[c][1,2,3]triazolo[1,5-a]azepine 

Relevant academic research and scientific papers

Synthesis of N-Alkyl Anilines from Arenes via Iron-Promoted Aromatic C-H Amination

We report both an intermolecular C-H amination of arenes to access N-methylanilines and an intramolecular variant for the synthesis of tetrahydroquinolines. A newly developed, highly electrophilic aminating reagent was key for the direct synthesis of unprotected N-methylanilines from simple arenes. The reactions display a broad functional group tolerance and employ catalytic amounts of a benign iron salt under mild reaction conditions.

Intramolecular Cycloaddition Approach to Fused Pyrazoles: Access to 4,5-Dihydro-2 H -pyrazolo[4,3- c ]quinolines, 2,8-Dihydroindeno[2,1- c ]pyrazoles, and 4,5-Dihydro-2 H -benzo[ e ]indazoles

A straightforward and efficient method for the synthesis of pyrazoles fused with 1,2,3,4-tetrahydroquinoline, 2,3-dihydro-1 H -indene, or 1,2,3,4-tetrahydronaphthalene involves the formation of the tosylhydrazone from an aromatic substrate carrying aldehy

Harnessing [1,4], [1,5], and [1,6] Anionic Fries-type Rearrangements by Reaction-Time Control in Flow

A series of anionic Fries-type rearrangements of carbamoyl-substituted aryllithium intermediates were controlled by using flow microreactor systems. For the [1,4] and [1,5] rearrangements, the aryllithium intermediate formed before carbamoyl migration and

A Direct Arylation-Cyclisation Reaction for the Construction of Medium-Sized Rings

A strategy for assembling biaryls linked through a medium-sized ring is herein presented. π-Complexation of fluoroarenes to chromium tricarbonyl activates the molecule towards both C?H activation and nucleophilic aromatic substitution without covalently a

Palladium-catalyzed double carbonylation-based diversity-oriented synthesis of 3,4-dihydroisoquinoline-1-carboxamides

Abstract A novel palladium-catalyzed double carbonylation approach toward the synthesis of 3,4-dihydroisoquinoline-1-carboxamides is reported. The method developed involves an initial palladium-catalyzed double carbonylation of an N-protected alkylamine a

Oxacycle synthesis via intramolecular reaction of carbanions and peroxides

The intramolecular reaction of dialkyl peroxides with carbanions, generated via chemoselective metal-heteroatom exchange or deprotonation, provides a new approach to cyclic ethers. Applied in tandem with C-C bond formation, the strategy enables a one-step annelation to form oxaospirocycles.

Facile synthesis of [1,2,3]-triazole-fused isoindolines, tetrahydroisoquinolines, benzoazepines and benzoazocines by palladium-copper catalysed heterocyclisation

An elegant method for the synthesis of 1,2,3-triazoles fused with five-, six-, seven- and eight-membered benzoheterocycles, including isoindoline, tetrahydroisoquinoline, benzoazepine and benzoazocine, has been developed via palladium-copper catalysed reactions in one-pot. The broad scope of this reaction was illustrated by effecting bis-heteroannulations, synthesis of uracil derivatives of biological interest, and employment of acetylene gas as an inexpensive substrate. The reactions are experimentally simple and utilise easily accessible substrates of different types. Georg Thieme Verlag Stuttgart · New York.

Highly diastereoselective radical cyclisations of chiral sulfinimines

Chiral amines are formed by the highly diastereoselective intramolecular addition of alkyl and aryl radicals onto chiral mesityl sulfinimines.

NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF

The invention relates to pyridinyl nicotinic acetylcholine receptor ligands, compositions comprising an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand and methods to treat or prevent a condition, such as depression and nicotine dependence, comprising administering to an animal in need thereof an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand.

Generation of medium-ring cycloalkynes by ring expansion of vinylogous acyl triflates

Reductive cyclization of aryl and vinyl iodides tethered to vinylogous acyl triflates (VATs) induces a ring-expanding fragmentation to provide cyclic alkynyl ketones, including strained nine-membered cycloalkynes, in fair to excellent yield. The tandem cy