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The chemical "2H-1-Benzopyran-2-one, 3,3'-(phenylmethylene)bis[4-hydroxy-" is a complex organic compound with the molecular formula C21H14O6. It is a derivative of 2H-1-benzopyran-2-one, also known as chromone, which is a heterocyclic compound with a benzene ring fused to a pyran ring. The compound features two 4-hydroxy chromone moieties connected by a phenylmethylene bridge, which is a phenyl group with a double bond to a methylene group. This structure gives the compound unique properties and potential applications in various fields, such as pharmaceuticals or materials science.

1821-19-8

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1821-19-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1821-19-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,2 and 1 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1821-19:
(6*1)+(5*8)+(4*2)+(3*1)+(2*1)+(1*9)=68
68 % 10 = 8
So 1821-19-8 is a valid CAS Registry Number.

1821-19-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-hydroxy-3-[(4-hydroxy-2-oxochromen-3-yl)-phenylmethyl]chromen-2-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1821-19-8 SDS

1821-19-8Relevant academic research and scientific papers

Regio and diastereoselective synthesis of functionalized 2,3-dihydrofuro[3,2-c]coumarins via a one-pot three-component reaction

Altieri, Elisa,Cordaro, Massimiliano,Grassi, Giovanni,Risitano, Francesco,Scala, Angela

, p. 9493 - 9496 (2010)

An efficient and straightforward synthesis of furo[3,2-c]coumarins via the one-pot three-component condensation of aromatic aldehydes, 4-hydroxycoumarin and α-chloroketones in refluxing n-propanol is described. Pyridine or a mixture of AcOH and AcONH4 was used as a basic catalyst.

Cytotoxic activity of new neodymium (III) complexes of bis-coumarins

Kostova, Irena,Manolov, Ilia,Momekov, Georgi

, p. 765 - 775 (2004)

Complexes of neodymium (III) with bis-coumarins: 3,3′-benzylidene- bis(4-hydroxy-2H-1-benzopyran-2-one); bis(4-hydroxy-2-oxo-2H-chromen-3-yl)- piridin-2-yl-methane; bis(4-hydroxy-2-oxo-2H-chromen-3-yl)-piridin-4-yl-methane; bis(4-hydroxy-2-oxo-2H-chromen-

Synthesis, photophysical properties, chemo-sensing ability and computational studies of biscoumarin derivatives

Harichandran, G.,Nehru, S.,Surya, C. P.

, (2021/09/20)

Synthesis of biscoumarin derivatives using an environment friendly,recyclable polymeric resin as catalyst via one-pot pseudo-three component reaction was simply achieved by using numerous substituted aromatic aldehydes (1 mM) and 4-hydroxycoumarin (2 mM)

Facile and Straightforward Synthesis of Racemic Version of Substituted 3-[3-(2-Hydroxyphenyl)-3-oxo-1-arylpropyl]-4-hydroxycoumarins: Easy Access to a Series of Biorelevant Warfarin Analogues

Brahmachari, Goutam,Mandal, Mullicka,Karmakar, Indrajit

, p. 451 - 464 (2021/10/19)

The present communication deals with a straightforward, efficient, and green synthesis of a series of racemic version of 3-[3-(2- hydroxyphenyl)-3-oxo-1-arylpropyl]-4-hydroxycoumarins as biologically interesting warfarin analogues upon decarboxylative hyd

Chitosan and functionalized graphene oxide nanocomposite as a novel and highly efficient catalyst for production of bis-coumarins under solvent-free conditions

Atashrouz, Zhale,Rostami, Esmael,Zare, Abdolkarim

, p. 179 - 201 (2021/11/18)

Chitosan and functionalized graphene oxide nanocomposite was used as efficient, sustainable, and recyclable catalyst in the production of bis-coumarins using 4-hydroxycoumarin and aromatic aldehydes under solvent-free conditions. Chitosan was first functi

Developing a highly potent anthelmintic: study of catalytic application of l-proline derived aminothiourea in rapid synthesis of biscoumarins and their in vitro anthelmintic essay

Kharrngi, Balamphrang,Dhar, Errini Decruse,Basumatary, Grace,Das, Dharitri,Deka, Ramesh Ch,Yadav, Arun K,Bez, Ghanashyam

, (2021/02/22)

Abstract: Due to serious side effects of benzimidazoles such as apoptosis and mitotic arrest, development of alternative anthelmintic drugs with comparable efficacy to target the acetylcholine receptors of parasites is considered very important to control

Unveiling the anti-tubercular properties of biscoumarins, through biological evaluation and docking studies

Acharya, Poornima,Ramana,Upadhyay, Manish,Pavale, Ganesh

, p. 57 - 66 (2021/02/27)

Background: Biscoumarin scaffolds are known for their promising pharmacological properties. These compounds have not been studied for their activity against tuberculosis strains. Objective: Unveil the antitubercular properties of biscoumarin scaffolds. Me

Bis [hydrazinium (1+)] hexafluoridosilicate:(N2H5)2SiF6 novel hybrid crystal as an efficient, reusable and environmentally friendly heterogeneous catalyst for Knoevenagel condensation and synthesis of biscoumari

El hajri, Fatima,Benzekri, Zakaria,Sibous, Sarra,Ouasri, Ali,Boukhris, Said,Hassikou, Amina,Rhandour, Ali,Souizi, Abdelaziz

, (2021/02/03)

A simple, effective, green and nontoxic protocol was used for the Knoevenagel condensation and the biscoumarin derivatives synthesis. It have demonstrated that the use of a new hybrid crystal as a heterogeneous catalyst makes it possible to obtain several

Recyclable Amberlite IR-120 Catalyzed domino reaction: Synthesis, anticancer activity and molecular docking studies of biscoumarins

Harish, B. G.,Ismail,Shadakshari, A. J.,Sowmya, H. B. V.,Suresha Kumara, T. H.,Yamuna, A. J.

, (2021/08/10)

Under mild conditions, an environmentally friendly method has been developed for the synthesis of bis-coumarins by using a reasonably lesser quantity of Amberlite IR-120 through Domino Knoevenagel–Michael reaction. In which, a series of aryl aldehydes hav

A synergetic role of Aegle marmelos fruit ash in the synthesis of biscoumarins and 2-amino-4H-chromenes

Patil, Rupesh C.,Shinde, Sachinkumar K.,Patil, Uttam P.,Birajdar, Appasaheb T.,Patil, Suresh S.

, p. 1675 - 1691 (2021/01/11)

Abstract: A dry rind of Aegle marmelos (bael) fruit ash as a synergetic alternative material to an expensive, toxic and corrosive catalysts for the synthesis of biscoumarins and 2-amino-4H-chromenes at ambient temperature in water is reported. The spectro

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