182169-63-7

Basic information

• Product Name: 1-(4'-METHOXY[1,1'-BIPHENYL]-3-YL)ETHANONE
• Synonyms: 1-(4'-METHOXY-BIPHENYL-3-YL)-ETHANONE;1-(4'-METHOXY[1,1'-BIPHENYL]-3-YL)ETHANONE;AKOS BAR-0239;1-[3-(4-methoxyphenyl)phenyl]ethanone
• CAS NO: 182169-63-7
• Molecular Formula: C15H14O2
• Molecular Weight: 226.27
• Mol File: 182169-63-7.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 383.4 °C at 760 mmHg
• Flash Point: 175.5 °C
• Appearance: /
• Density: 1.076 g/cm³
• CAS DataBase Reference: 1-(4'-METHOXY[1,1'-BIPHENYL]-3-YL)ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4'-METHOXY[1,1'-BIPHENYL]-3-YL)ETHANONE(182169-63-7)
• EPA Substance Registry System: 1-(4'-METHOXY[1,1'-BIPHENYL]-3-YL)ETHANONE(182169-63-7)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 182169-63-7(Hazardous Substances Data)

Usage

General Description

1-(4'-Methoxy[1,1'-biphenyl]-3-yl)ethanone, also known as 4'-Methoxy-1,1-biphenyl-3-ylacetone, is an organic compound and a ketone derivative. It is a white crystalline solid with a sweet, fruity odor. This chemical is used in various industries, including as a fragrance ingredient in perfumes and in the production of pharmaceuticals and other organic compounds. It is also a valuable intermediate in the synthesis of various organic molecules. Additionally, 1-(4'-Methoxy[1,1'-biphenyl]-3-yl)ethanone has potential applications in the field of organic chemistry research and as a building block for the development of new materials and compounds. Despite its potential uses, it is important to handle this chemical with care and follow safety protocols due to its potential hazards.

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Relevant articles and documents

Dual-Metal N-Heterocyclic Carbene Complex (M = Au and Pd)-Functionalized UiO-67 MOF for Alkyne Hydration-Suzuki Coupling Tandem Reaction

Metal N-heterocyclic carbene complexes (NHC-M) have been recognized as an important class of organometallic catalysts. Herein, we demonstrate that different NHC-M (M = Au and Pd) species can be simultaneously introduced into a single metal organic framework (MOF) by direct assembly of NHC-M-decorated ligands and metal ions under solvothermal conditions. The obtained UiO-67-Au/Pd-NHBC MOF with different organometallic NHC-M species can be a highly reusable dual catalyst to sequentially promote alkyne hydration-Suzuki coupling reaction. The potential utility of this strategy is highlighted by the preparation of many more new multicatalysts of this type for various organic transformations in a sequential way.

Reusable Palladium N-Heterocyclic Tetracarbene for Aqueous Suzuki-Miyaura Cross-Coupling Reaction: Homogeneous Catalysis and Heterogeneous Recovery

A pH-responsive Pd(II) N-heterocyclic tetracarbene complex synthesized by a solvothermal method was reported. It can be a highly active reusable catalyst to homogeneously catalyze the Suzuki-Miyaura cross-coupling reaction in water and can be heterogeneously recovered by simply adjusting the pH value of the aqueous reaction media.

Palladium(II) Chloride Complexes of N,N′-Disubstituted Imidazole-2-thiones: Syntheses, Structures, and Catalytic Performances in Suzuki-Miyaura and Sonogashira Coupling Reactions

Reactions of PdCl2 with 2 equiv of N,N′-disubstituted-imidazole-2-thiones R1R2C3N2S (R1 = R2 = Me (1a), iPr (1b), Cy (1c), C6Me3H2 (1d); R1 = Me, R2 = Ph (1e)) under the different conditions afford five mononuclear complexes trans-[(R1R2C3N2S)2PdCl2] (R1 = R2 = Me (2a), iPr (2b), Cy (2c), C6Me3H2 (2d); R1 = Me, R2 = Ph (2e)) and five binuclear Pd(II) complexes [(PdCl2){μ-(R1R2C3N2S)}]2 (R1 = R2 = Me (3a), iPr (3b), Cy (3c), C6Me3H2 (3d); R1 = Me, R2 = Ph (3e)), respectively. Complexes 2a-2e are easily converted into the corresponding 3a-3e by adding equimolar PdCl2 in refluxing MeOH, while the reverse reaction is achieved at room temperature by addition of 2 equiv of 1a-1e. In 2b, 2d, and 2e, each Pd(II) holds a distorted square planar geometry completed by two trans Cl atoms and two trans S atoms. Complexes 3a-3e have a dimeric [Pd2S2] structure in which two {PdCl2} units are interlinked by two N,N′-disubstituted-imidazole-2-thiones. Each Pd(II) adopts a distorted square planar geometry accomplished by two cis Cl atoms and two cis bridging S atoms. Among them, complex 3d has the two largest C6Me3H2 groups on the 2 and 5 positions of imidazole-2-thione, the longest Pd-μ-S bond, the largest S-Pd-S angle, and displays the highest catalytic activity toward Suzuki-Miyaura and copper-free Sonogashira cross-coupling reactions, which are confirmed by density functional theory calculations. The results provide an interesting insight into the introduction of various substituent groups into the periphery ligands of coordination complex-based catalysts, which could tune their geometric structures to acquire the best catalytic activity toward organic reactions.