182188-92-7 Usage
Classification
Thiazolidine compound
Functional groups
Piperidine group, chlorophenyl group
Therapeutic uses
Stimulant, anorectic agent
Reported effects
Similar to amphetamines
Medical uses
Treatment of narcolepsy and depression
Adverse effects
Increased heart rate, hypertension, psychiatric symptoms
Controlled substance status
Some countries classified it as such
Abuse potential
Due to its effects, it has potential for abuse.
Check Digit Verification of cas no
The CAS Registry Mumber 182188-92-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,2,1,8 and 8 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 182188-92:
(8*1)+(7*8)+(6*2)+(5*1)+(4*8)+(3*8)+(2*9)+(1*2)=157
157 % 10 = 7
So 182188-92-7 is a valid CAS Registry Number.
InChI:InChI=1/C24H29ClN2O2S/c1-18-3-5-19(6-4-18)23-27(22(28)17-30-23)14-2-13-26-15-11-24(29,12-16-26)20-7-9-21(25)10-8-20/h3-10,23,29H,2,11-17H2,1H3
182188-92-7Relevant articles and documents
Synthesis and pharmacological activity of 2-(substituted phenyl)-3{2 or 3-[(4-substituted phenyl-4-hydroxy)piperidino]ethyl or propyl}-1,3- thiazolidin-4-ones
Diurno,Mazzoni,Capasso,Izzo,Bolognese
, p. 237 - 241 (2007/10/03)
A series of aryl-hydroxy-piperidinoalkyl-thiazolidinones was synthesized and evaluated to inhibit castor oil-induced diarrhea in mice. The dose dependent antidiarrheal activity of the most active compound 2-(p- nitrophenyl)-3-[2-[(4-(p-chlorophenyl)-4-hydroxy)piperidino]ethyl]-1,3- thiazolidin-4-one (6) was counteracted by naloxone, resulting comparable with that of loperamide, a μ opiate agonist.
