1822-49-7

Basic information

• Product Name: 2-(2-Pyridiniomethyl)isothiouronium dichloride
• Synonyms: pyridin-2-ylmethyl carbamimidothioate dihydrochloride;EINECS 217-349-1;2-pyridin-2-ylmethyl-isothiourea-dihydrochloride
• CAS NO: 1822-49-7
• Molecular Formula: C7H11Cl2N3S
• Molecular Weight: 240.156
• Mol File: 1822-49-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(2-Pyridiniomethyl)isothiouronium dichloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Pyridiniomethyl)isothiouronium dichloride(1822-49-7)
• EPA Substance Registry System: 2-(2-Pyridiniomethyl)isothiouronium dichloride(1822-49-7)

Safety Data

• Hazardous Substances Data: 1822-49-7(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic compound

Contains

Pyridine ring and thiouronium group

Solubility

Water-soluble salt

Uses

Reagent in organic synthesis, catalyst in chemical reactions

Functionality

Ability to transfer a methylthio group to various substrates

Applications

Synthesis of sulfur-containing compounds, preparation of pharmaceuticals and agrochemicals

Fields of use

Medicinal chemistry, material science, and chemical biology

Upstream product

• 76732-85-9 2-(5-methylpyrid-2-ylmethyl)isothiourea dihydrochloride 
• 109-70-6 1.3-chlorobromopropane 
• 76732-82-6 2-(4-methylpyrid-2-ylmethyl)isothiourea dihydrochloride 
• 6959-47-3 2-chloromethylpyridine hydrochloride 
• 17356-08-0 thiourea 

Downstream Products

• 2044-73-7 2-(sulfanylmethyl)pyridine 
• 76743-03-8 2-Pyridin-2-yl-tetrahydro-thiophene-2-carbothioic acid benzylamide 
• 104489-64-7 2-Pyridin-2-yl-tetrahydro-thiophene-2-carbothioic acid phenylamide 
• 76732-75-7 N-methyl-2-(2-pyridyl)tetrahydrothiophene-2-carbothioamide 
• 76732-76-8 2-(2-pyridyl)tetrahydrothiophene 

Relevant articles and documents

Synthesis of Isothiourea Derivatives

The reaction of thioureas (9) with 2-chloromethylpyridine hydrochloride (5), 3-chloromethylpyridine hydrochloride (6), 2-chloromethylquinoline hydrochloride (7), and 5-chloromethyl-4-methylimidazole hydrochloride (8) gave the isothiourea dihydrochlorides

2-(Pyrid-2-yl)tetrahydrothiophene derivatives

Compounds of the formula: STR1 wherein R represents hydrogen or alkyl of 1 through 4 carbon atoms, and R1 and R2 represent hydrogen or alkyl of 1 through 15 carbon atoms, or alkyl of 1 through 15 carbon atoms substituted by one substituent selected from (i) hydroxy, (ii) alkylamino in which the alkyl radical is of 1 through 4 carbon atoms, (iii) dialkylamino in which the alkyl radicals are of 1 through 4 carbon atoms, (iv) phenyl, (v) carboxy, and (vi) alkoxycarbonyl in which the alkoxy radical is of 1 through 4 carbon atoms, or R1 and R2 together with the nitrogen atom to which they are attached represent a five- or six-membered heterocyclic radical, are new compounds. They possess pharmacological properties and are particularly useful in the treatment of gastro-intestinal ulcers.