18231-00-0Relevant articles and documents
NEW GLYCOLIPIDS AND USE THEREOF AS SK3 ION CHANNEL MODULATORS
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Page/Page column 40-41, (2022/01/24)
The present invention relates to new glycolipids derivatives of Formula (I) and their use in the treatment of diseases related with a deregulation of the expression and/or activity of SK3 ion channels. The present invention further relates to pharmaceutical compositions comprising compounds of Formula (I) for use in the treatment of diseases related with a deregulation of the expression and/or activity of SK3 ion channels.
Flexible metathesis-based approaches to highly functionalised furans and pyrroles
Donohoe, Timothy J.,Kershaw, Neil M.,Orr, Allan J.,Wheelhouse, Katherine M.P.,Fishlock, Lisa?P.,Lacy, Adam R.,Bingham, Matilda,Procopiou, Panayiotis A.
, p. 809 - 820 (2008/09/16)
A range of differentially functionalised furans and pyrroles have been synthesised in short order by the judicious use of a ring-closing metathesis/aromatisation strategy. Two contrasting approaches are described exploiting a palladium-catalysed union of
Macrocyclic kinase inhibitors
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Page/Page column 78, (2010/02/14)
Compounds having the formula are useful for inhibiting protein kinases. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
