182319-86-4

Upstream product

• 182319-85-3 N-(4-methoxybenzenesulfonyl)-O-benzyl-D-valine 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 161315-45-3 N-[4-methoxybenzenesulfonyl]-(D)-valine 
• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 
• 640-68-6 D-Val-OH 

Downstream Products

• 1092690-88-4 N-(4-methoxybenzenesulfonyl)-N-tert-butoxycarbonylmethyl-D-valine 
• 1092690-91-9 N-(4-methoxybenzenesulfonyl)-N-tert-butoxycarbonylmethyl-O-benzyl-D-valinehydroxamic acid 
• 1092690-94-2 (R)-2-(N-(1-(benzyloxyamino)-3-methyl-1-oxobutan-2-yl)-4-methoxyphenylsulfonamido)acetic acid 
• 1203834-92-7 (R)-1-hydroxy-3-isopropyl-4-(4-methoxyphenylsulfonyl)piperazine-2,6-dione 
• 1203835-05-5 (R)-1-(benzyloxy)-3-isopropyl-4-(4-methoxyphenylsulfonyl)piperazine-2,6-dione 

Relevant academic research and scientific papers

Novel 1-hydroxypiperazine-2,6-diones as new leads in the inhibition of metalloproteinases

New compounds containing a novel zinc-binding group (1-hydroxypiperazine-2, 6-dione, HPD) have been identified as effective inhibitors of matrix metalloproteinases (MMPs), with activities in the nanomolar concentration range. That moiety seemed to bind th

Dual inhibitors of matrix metalloproteinases and carbonic anhydrases: Iminodiacetyl-based hydroxamate-benzenesulfonamide conjugates

Matrix metalloproteinases (MMPs) and carbonic anhydrases (CAs) are two classes of zinc enzymes with different roles and catalytic targets, such as the degradation of most of the extracellular matrix (ECM) proteins and the regulation of the CO2/