182417-58-9

Basic information

• Product Name: (R)-3-hydroxy-5-phenyl-pentanoic acid ethyl ester
• Synonyms: (R)-3-hydroxy-5-phenyl-pentanoic acid ethyl ester
• CAS NO: 182417-58-9
• Molecular Weight: 222.284
• Mol File: 182417-58-9.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (R)-3-hydroxy-5-phenyl-pentanoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-hydroxy-5-phenyl-pentanoic acid ethyl ester(182417-58-9)
• EPA Substance Registry System: (R)-3-hydroxy-5-phenyl-pentanoic acid ethyl ester(182417-58-9)

Safety Data

• Hazardous Substances Data: 182417-58-9(Hazardous Substances Data)

Upstream product

• 17071-29-3 ethyl 3-oxo-5-phenylpentanoate 
• 104-53-0 3-phenyl-propionaldehyde 
• 623-48-3 ethyl iodoacetae 
• 55282-95-6 ethyl (2E)-5-phenylpent-2-enoate 
• 88842-13-1 (Z-)-ethyl 5-phenylpent-2-enoate 
• 1006696-14-5 ethyl 5-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pentanoate 
• 100-39-0 benzyl bromide 
• 141-97-9 ethyl acetoacetate 
• 53376-62-8 ethyl 3-hydroxy-5-phenylpentanoate 
• 1198356-01-2 (R)-ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-phenylpentanoate 

Downstream Products

• 153744-07-1 (R)-3-hydroxy-5-phenylvaleric acid 
• 465545-16-8 (3R)-ethyl 5-phenyl-3-trimethylsilyloxy-pentanoate 
• 918148-51-3 t-butyl (R)-5-hydroxy-3-oxo-7-phenylheptanoate 
• 86117-01-3 (4R,6R)-(+)-4-hydroxy-6-(2-phenylethyl)-tetrahydro-2H-pyran-2-one 
• 116332-80-0 (2R,6R)-2-(tert-butyl)-6-(2'-phenylethyl)-1,3-dioxan-4-one 
• 465545-17-9 (R)-5-Phenyl-3-trimethylsilanyloxy-pentanal 

Relevant articles and documents

Asymmetric synthesis of (6R)-4-hydroxy-6-substituted-δ-lactones

A novel approach for the asymmetric synthesis of (6R)-4-hydroxy-6-substituted-δ-lactones has been achieved using asymmetric reduction of a prochiral ketone in the presence of (S)-(?)-diphenyl-prolinol/borane as a key step. The enantiomeric purity of the products was determined by chiral GC.

Asymmetric β-boration of α,β-unsaturated carbonyl compounds with chiral Rh[bis(oxazolinyl)phenyl] catalysts

Chiral rhodium[bis(oxazolinyl)phenyl] complexes exhibited high catalytic activity for the β-boration of α,β-unsaturated esters, ketones, and amides with bis(pinacolato)diboron in the presence of sodium tert-butoxide to attain high enantioselectivity of up to 97%. The substrate scope and catalytic mechanism were discussed.

Asymmetric β-boration of α,β-unsaturated carbonyl compounds promoted by chiral rhodium-bisoxazolinylphenyl catalysts

Chiral rhodium-bisoxazolinylphenyl acetate complexes exhibited high catalytic activity for the β-boration of α,β-unsaturated carbonyl compounds with bis(pinacolato)diboron in the presence of sodium t-butoxide with enantioselectivity up to 97%.