18247-80-8

Basic information

• Product Name: N-(4-Nitrophenyl)-2-oxopropanehydrazonic acid chloride
• Synonyms: 1-(1-Chloro-2-oxopropylidene)-2-(p-nitrophenyl)hydrazine;1-Chloro-1-[2-(4-nitrophenyl)hydrazono]-2-propanone;N-(4-Nitrophenyl)-2-oxopropanehydrazonic acid chloride
• CAS NO: 18247-80-8
• Molecular Formula: C₉H₈ClN₃O₃
• Molecular Weight: 241.6311
• Mol File: 18247-80-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 380.2°Cat760mmHg
• Flash Point: 183.7°C
• Appearance: /
• Density: 1.42g/cm³
• Vapor Pressure: 5.56E-06mmHg at 25°C
• Refractive Index: 1.606
• CAS DataBase Reference: N-(4-Nitrophenyl)-2-oxopropanehydrazonic acid chloride(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-Nitrophenyl)-2-oxopropanehydrazonic acid chloride(18247-80-8)
• EPA Substance Registry System: N-(4-Nitrophenyl)-2-oxopropanehydrazonic acid chloride(18247-80-8)

Safety Data

• Hazardous Substances Data: 18247-80-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H8ClN3O3/c1-6(14)9(10)12-11-7-2-4-8(5-3-7)13(15)16/h2-5,11H,1H3

Upstream product

• 67-56-1 methanol 
• 2684-62-0 diazoacetone 
• 100-05-0 4-nitrobenzenediazonium chloride 
• 67-66-3 chloroform 
• 7782-50-5 chlorine 
• 50711-98-3 pentane-2,3,4-trione-3-(4-nitro-phenylhydrazone) 
• 18804-75-6 1-(2-(4-nitrophenyl)hydrazono)propan-2-one 
• 100-01-6 4-nitro-aniline 
• 1694-29-7 3-chloropentane-2,4-dione 

Downstream Products

• 128671-13-6 1-(5-Amino-[1,2,4]triazol-1-yl)-1-[(4-nitro-phenyl)-hydrazono]-propan-2-one 
• 1063737-38-1 C₂₂H₁₅N₃O₄S 
• 1063737-27-8 C₂₂H₁₅N₃O₃S₂ 
• 1177417-12-7 3-acetyl-1-(4-nitrophenyl)-6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-5-one 
• 1220453-25-7 1-[4-benzoyl-1-(4-nitrophenyl)-1H-pyrazol-3-yl]-ethanone 
• 178615-97-9 3-acetyl-4-benzoyl-1-(4-nitrophenyl)-5-phenyl-1H-pyrazole 
• 1333972-83-0 6-acetyl-3,5-diphenyl-8-(4-nitrophenyl)-5,8-dihydro-[1,2,4]triazolo[4,3-b][1,2,4,5]tetrazine 
• 1360830-36-9 3-acetyl-5,7-dimethyl-1-(4-nitrophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione 
• 1426562-07-3 4-methylbenzaldehyde N-[1-(4-nitrophenyl)-3-acetyl-4-cyanopyrazol-5-yl]hydrazone 
• 1426561-98-9 4-chlorobenzaldehyde N-[1-(4-nitrophenyl)-3-acetyl-4-cyanopyrazol-5-yl]hydrazone 
• 1426561-94-5 3-amino-7-methyl-2-(4-nitrophenyl)-2,5-dihydro-4-oxopyrazolo[3,4-d]pyridazine 
• 58131-66-1 1-[5-ethoxy-1-(4-nitro-phenyl)-1H-pyrazol-3-yl]-ethanone 
• 128671-05-6 (2-Methyl-6-phenyl-1H-imidazo[1,2-b]pyrazol-3-yl)-(4-nitro-phenyl)-diazene 
• 128671-15-8 C₂₄H₂₀N₆O₃ 

Relevant articles and documents

Synthesis and cytotoxic activity study of novel 2-(Aryldiazenyl)-3-methyl-1h-benzo[g]indole derivatives

A novel series of 2-(aryldiazenyl)-3-methyl-1H-benzo[g]indole derivatives (3a–f) were prepared through the cyclization of the corresponding arylamidrazones, employing polyphosphoric acid (PPA) as a cyclizing agent. All of the compounds (3a–f) were characterized using1H NMR,13C NMR, MS, elemental analysis, and melting point techniques. The synthesized compounds were evaluated for cytotoxic activity against diverse human cancer cell lines by the National Cancer Institute. While all of the screened compounds were found to be cytotoxic at a 10 μM concentration, two of them (2c) and (3c) were subjected to five dose screens and showed a significant cytotoxicity and selectivity.

Application of phenylhydrazine base ketone compound as agricultural bactericide

The invention relates to an application of phenylhydrazine base ketone compound as agricultural bactericide, the application of the phenylhydrazine base ketone compound disclosed in a formula (1) for inhibiting or killing fungi which cause crop diseases and the application of the phenylhydrazine base ketone compound as the agricultural bactericide. The phenylhydrazine base ketone compound has the advantage of high activity when being used for inhibiting the fungi which cause crop diseases to grow, is suitable for preventing and curing plant diseases caused by the fungi and can be used for preventing and curing diseases caused by various fungi including rice blast and wheat scab, wherein R1, R2, R3, R4 and R5 are respectively independently selected from hydrogen, halogen, alkyl group, alkoxy, hydroxyl, cyanogroup, trifluoromethyl, sulfamide and nitryl; R6 is selected from hydrogen, halogen, alkyl group, amino, cyanogroup, CH3CH2S-, CH3CO-, CF3CH2CO- or CF3CO- and the like; R7 is alkyl group, hydroxyl, phenyl, halogenated phenyl, alkoxy and trifluoromethyl; X can be nitrogen or carbon, and R5 is not in the presence when X is nitrogen, the formula (1) is shown in the description.