Tetrahedron Letters p. 7339 - 7342 (1996)
Update date:2022-08-11
Topics:
Bernotas, Ronald C.
Adams, Ginette
A novel 1-benzylpiperazin-2-one nitrone has been synthesized. It readily undergoes [3 + 2] cycloadditions with alkynes and alkenes to give Δ4-isoxazolines and isoxazolidines, respectively, which can be reductively opened to 3-substituted piperazin-2-ones and 1,3-amino alcohols.
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