1833-18-7

Upstream product

• 141-52-6 sodium ethanolate 
• 622-73-1 4-methoxybenzaldehydephenylhydrazone 
• 110-46-3 isopentyl nitrite 
• 27402-47-7 5-benzylidenebarbituric acid 
• 1753-47-5 5-(4-dimethylaminobenzylidene)barbituric acid 
• 49546-71-6 5-(4-methoxybenzylidene)barbituric acid 

Downstream Products

• 67400-58-2 3,5-bis(4-methoxyphenyl)-1-phenyl-1H-1,2,4-triazole 

Relevant academic research and scientific papers

Reaction 5-(Arylmethylidene)-2,4,6-pyrimidine-2,4,6(1H,3H,5H)-triones with Arenecarbaldehyde Phenylhydrazones in the Presence of Sodium N-Chlorobenzenesulfonamide

The reactions of 5-(arylmethylidene)-2,4,6-pyrimidine-2,4,6(1H,3H,5H)-triones with arenecarbaldehyde phenylhydrazones in the presence of sodium N-chlorobenzenesulfonamide give 2,3,7,9-tetraasaspiro-[4.5]dec-1-ene-6,8,10-triones in yields of 30–45%.

Copper(II)-catalyzed aerobic oxidative synthesis of substituted 1,2,3- and 1,2,4-triazoles from bisarylhydrazones via C-H functionalization/C-C/N-N/C-N bonds formation

An unprecedented copper(II)-catalyzed aerobic oxidative synthesis of 2,4,5-triaryl-1,2,3-triazoles and 1,3,5-triaryl-1,2,4-triazoles from bisarylhydrazones as the common starting precursor has been achieved via cascade C-H functionalization/C-C/N-N/C-N bonds formation under mild reaction conditions. One of the enthralling outcomes of this strategy is the copper(II)-catalyzed room temperature C-H functionalization/C-N bond formation in presence of air, which has been accomplished during the synthesis of substituted 1,2,4-triazoles. This new class of compounds could give prospective luminescence as an iconic component in the area of pharmaceutical and biological sciences. The intermediates for both the processes have been isolated to elucidate the mechanistic scenario.