18427-47-9

Upstream product

• 10458-14-7 (2R,5S)-menthone 
• 1196-31-2 (1R,4R)-(+)-isomenthone 
• 55985-69-8 4-bromo-p-menthan-3-one 
• 10458-14-7 Menthone 
• 67-66-3 chloroform 
• 7726-95-6 bromine 

Downstream Products

• 89-83-8 thymol 
• 54783-36-7 ξ-diosphenol 
• 30313-90-7 4,4',4''-trithymylmethane 
• 84817-96-9 tris-(4-acetoxy-5-isopropyl-2-methyl-phenyl)-methane 
• 490-03-9 2-hydroxy-1-p-menthen-3-one 
• 60507-82-6 (6R)-(+)-Ψ-diosphenol 
• 468722-73-8 (6S)-(-)-Ψ-diosphenol 

Relevant academic research and scientific papers

Stereoselective synthesis of (6R)- and (6S)-diosphenol and Ψ-diosphenol

Methods are discussed for the stereoselective synthesis of the (R)-and (S)-enantiomers of the diosphenols (5)-(8) by utilizing the commercially available stereoisomers (9), (12), (23) and (25) of carvone and limonene, respectively, as chiral starting materials.

Formation of an Unusual Trimer During Preparation of Thymol

In the dehydrodehalogenation of 2,4-dibromomenthone, in both acidic and alkaline media, in addition to thymol two other minor products are also obtained.One of them is shown to be a novel alkylation product and characterised as 4,4',4''-trioxy-2,2',2''-trimethyl-5,5',5''-triisopropyltriphenylmethane (4,4',4''-trithymylmethane) on the basis of chemical and spectroscopic data.

CONVENIENT PREPARATION OF 1,2-CYCLOHEXANEDIONES

1,2-Cyclohexanedione and 3-alkyl-1,2-cyclohexanediones were prepared in good to excellent yields from the corresponding 2,6-dibromocyclohexanones by treatment with aqueous NaOH.