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2-Hydroxy-6-(isopropyl)-3-methylcyclohex-2-en-1-one, also known as buchu leaf ketone, is a cyclic monoterpene ketone derived from buchu leaf and buchu leaf oil. It is characterized by its colorless to pale yellow crystalline appearance and its strong, herbal aroma reminiscent of minty buchu leaves and black currant. 2-hydroxy-6-(isopropyl)-3-methylcyclohex-2-en-1-one is known for its high strength odor and is recommended to be smelled in a 0.1% solution or less.

490-03-9

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490-03-9 Usage

Uses

Used in Flavor and Fragrance Industry:
2-Hydroxy-6-(isopropyl)-3-methylcyclohex-2-en-1-one is used as a flavoring agent for its minty and black currant aroma, adding a unique and pleasant scent to various food and beverage products.
Used in Aromatherapy:
Due to its strong herbal aroma, 2-hydroxy-6-(isopropyl)-3-methylcyclohex-2-en-1-one can be used in aromatherapy as a natural alternative to synthetic fragrances, providing a soothing and refreshing experience.
Used in Perfumery:
2-hydroxy-6-(isopropyl)-3-methylcyclohex-2-en-1-one can be utilized as a key ingredient in the creation of perfumes and colognes, contributing to a complex and long-lasting scent profile.
Used in Cosmetics:
2-Hydroxy-6-(isopropyl)-3-methylcyclohex-2-en-1-one can be employed in the cosmetics industry to add a distinct and appealing fragrance to products such as lotions, creams, and shampoos.
Used in the Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, the strong aroma and unique chemical properties of 2-hydroxy-6-(isopropyl)-3-methylcyclohex-2-en-1-one may potentially be explored for its applications in the pharmaceutical industry, such as in the development of new drugs or as a component in drug delivery systems. Further research would be required to determine its suitability and efficacy in this context.

Synthesis Reference(s)

Journal of the American Chemical Society, 79, p. 4465, 1957 DOI: 10.1021/ja01573a059

Check Digit Verification of cas no

The CAS Registry Mumber 490-03-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,9 and 0 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 490-03:
(5*4)+(4*9)+(3*0)+(2*0)+(1*3)=59
59 % 10 = 9
So 490-03-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H16O2/c1-6(2)8-5-4-7(3)9(11)10(8)12/h6,8,11H,4-5H2,1-3H3

490-03-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name diosphenol

1.2 Other means of identification

Product number -
Other names 2-hydroxy-3-methyl-6-propan-2-ylcyclohex-2-en-1-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Food additives -> Flavoring Agents
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:490-03-9 SDS

490-03-9Relevant academic research and scientific papers

Stereoselective synthesis of (6R)- and (6S)-diosphenol and Ψ-diosphenol

Schneider, David F,Viljoen, Murray S

, p. 5307 - 5315 (2007/10/03)

Methods are discussed for the stereoselective synthesis of the (R)-and (S)-enantiomers of the diosphenols (5)-(8) by utilizing the commercially available stereoisomers (9), (12), (23) and (25) of carvone and limonene, respectively, as chiral starting materials.

Synthesis of naturally occurring diosphenols and hydroxydiosphenols

Schneider, David F.,Viljoen, Murray S.

, p. 1285 - 1292 (2007/10/03)

Syntheses of diosphenol (3), ψ-diosphenol (4), 6-hydroxydiosphenol (5) and 6-hydroxy-ψ-diosphenol (6), which are constituents of the essential oil from Barosma betulina Bartl. (mountain buchu), are discussed.

Synthesis of annulated 4-alkylidenebutenolides from natural occurring diosphenols

Schneider, David F.,Viljoen, Murray S.

, p. 3349 - 3360 (2007/10/03)

Diosphenol (3) and Ψ-diosphenol (4), two constituents of the essential oil from the buchu plant, Borosma betulina (Bartl.), were utilized for the synthesis of the anulated 4-ylidenebutenolides (5) and (6).

Synthesis of 2,3-Dimethoxy-p-cymene

Wahidullah, Solimabi,Paknikar, S. K.

, p. 880 - 881 (2007/10/02)

A simple and straightforward synthesis of the title compound (1) is described starting from menthone (2).The synthetic 2,3-dimethoxy-p-cymene (1) is not identical with the natural product reported by Zutshi and Bokadia .

Reaction of Singlet Oxygen with Enamino Carbonyl Systems. A General Method for the Synthesis of α-Keto Derivatives of Lactones, Esters, Amides, Lactams, and Ketones

Wasserman, Harry H.,Ives, Jeffrey L.

, p. 3573 - 3580 (2007/10/02)

A general method for the introduction of a ketone α to the carbonyl group of a ketone, lactone. ester, substituted amide, or lactam has been developed involving the formation and dye-sensitized photooxygenation of enamino carbonyl intermediates.

REGIOSELECTIVE MONOALKYLATION OF 3-METHYL-1,2-CYCLOHEXANEDIONE

Utaka, Masanori,Hojo, Makoto,Takeda, Akira

, p. 445 - 448 (2007/10/02)

Monoalkylation of 3-methyl-1,2-cyclohexanedione was achieved regioselectively to give 6-alkyl-3-methyl-1,2-cyclohexanedione as a major product without the formation of O-alkylated or polyalkylated products.

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