1847-68-3Relevant academic research and scientific papers
Combined Photoredox/Enzymatic C?H Benzylic Hydroxylations
Betori, Rick C.,May, Catherine M.,Scheidt, Karl A.
, p. 16490 - 16494 (2019/11/03)
Chemical transformations that install heteroatoms into C?H bonds are of significant interest because they streamline the construction of value-added small molecules. Direct C?H oxyfunctionalization, or the one step conversion of a C?H bond to a C?O bond, could be a highly enabling transformation due to the prevalence of the resulting enantioenriched alcohols in pharmaceuticals and natural products,. Here we report a single-flask photoredox/enzymatic process for direct C?H hydroxylation that proceeds with broad reactivity, chemoselectivity and enantioselectivity. This unified strategy advances general photoredox and enzymatic catalysis synergy and enables chemoenzymatic processes for powerful and selective oxidative transformations.
Manganese-catalyzed ring-opening carbonylation of cyclobutanol derivatives
Meyer, Tim,Yin, Zhiping,Wu, Xiao-Feng
supporting information, p. 864 - 867 (2019/02/20)
Herein, we report a manganese-catalyzed ring-opening carbonylation of cyclobutanol derivatives through cyclic C–C bond cleavage. The reaction happens via a radical-mediated pathway to selectively generate 1,5-ketoesters. A variety of substrates with subst
Asymmetric iodolactonization utilizing chiral squaramides
Tungen, Jorn E.,Nolsoe, Jens M. J.,Hansen, Trond V.
supporting information, p. 5884 - 5887 (2013/02/23)
Asymmetric iodolactonization of γ- and δ-unsaturated carboxylic acids has been explored in the presence of six different chiral organocatalysts 5-8. The catalyst 6b was found to facilitate the cyclization of 5-arylhex-5-enoic acids 1 to the corresponding
Gold-catalysed cyclic ether formation from diols
Jiang, Xiaolu,London, Emma K.,Morris, David J.,Clarkson, Guy J.,Wills, Martin
supporting information; experimental part, p. 9828 - 9834 (2011/02/23)
Gold(I) and (III) salts have been found to be highly effective at the catalysis of ether formation from alcohols. Intramolecular ether formation of a 1,5-diol was also achieved, with a stereoselectivity that indicates that an SN1 mechanism predominates. In an attempt to form a seven-membered ring, a stable 14-membered dimer product was also formed. Attempts to control the diastereoselectivity of the reaction using a chiral anionic counterion did not give products with a high de.
Increasing the open circuit voltage of bulk-heterojunction solar cells by raising the LUMO level of the acceptor
Kooistra, Floris B.,Knol, Joop,Kastenberg, Fredrik,Popescu, Lacramioara M.,Verhees, Wiljan J. H.,Kroon, Jan M.,Hummelen, Jan C.
, p. 551 - 554 (2007/10/03)
We report the synthesis, characterization, and electrochemical properties of ten new fullerene derivatives for usage in organic solar cells. The phenyl ring of PCBM was substituted with electron-donating and electron-withdrawing substituents to study thei
A general and straightforward approach to α,ω-ketoesters
Babudri, Francesco,Fiandanese, Vito,Marchese, Giuseppe,Punzi, Angela
, p. 13513 - 13520 (2007/10/03)
Chemoselective cross-coupling reactions of monoesters of dicarboxylic acid chlorides with organocopper reagents derived from Grignard reagents, cuprous bromide, and lithium bromide, provide a simple and straightforward method for synthesizing a variety of ketoesters.
Aspects of Tautomerism. Part 15. Investigations on Oxo-participation in δ-Oxocarboxylic Acid Chlorides during their Formation and Alcoholysis
Shashidhar, M. Srikantaiah,Bhatt, M. Vivekananda
, p. 355 - 358 (2007/10/02)
Oxalyl chloride converts ring-substituted 4-benzoylbutyric acids into a mixture of normal and pseudoacid chlorides by two independent and competing pathways.Pseudoacid chlorides are formed by a concerted 2?+2?+2? pathway.I
