18523-16-5

Upstream product

• 339199-98-3 1,3,5-trinitro-2,4,6-triphenoxy-benzene 
• 124-41-4 sodium methylate 
• 6284-83-9 1,3,5-trichloro-2,4-dinitrobenzene 
• 860556-89-4 3-chloro-1,5-dimethoxy-2,4-dinitro-benzene 
• 4328-17-0 trinitrophloroglucinol 
• 149-73-5 trimethyl orthoformate 
• 67-56-1 methanol 
• 107-31-3 Methyl formate 
• 1228939-33-0 5-methoxystyphnic acid 
• 621-23-8 1,2,3-trimethoxybenzene 
• 186581-53-3 diazomethane 
• 861081-00-7 1-chloro-3,5-dimethoxy-2,4-dinitro-benzene 
• 871880-52-3 1-chloro-3,5-dimethoxy-2,4,6-trinitrobenzene 
• 71-43-2 benzene 

Downstream Products

• 3058-38-6 2,4,6-triamino-1,3,5-trinitrobenzene 
• 132699-69-5 N,N',N''-Triisopropyl-2,4,6-trinitro-benzene-1,3,5-triamine; compound with isopropylamine 
• 132699-67-3 1,3,5-Tris<(2,2-dimethyl)propylamino>-2,4,6-trinitrobenzene 
• 68959-41-1 1,3,5-triethoxy-2,4,6-trinitrobenzene 

Relevant academic research and scientific papers

Preparation method of 1,3,5-trialkoxy-2,4,6-trinitrobenzene

The invention discloses a preparation method of 1,3,5-trimethoxy-2,4,6-trinitrobenzene. The method comprises the following steps: dissolving trinitrophloroglucinol in an alkylating reagent with the mass being 5 times that of the trinitrophloroglucinol to obtain a raw material solution; pumping the raw material solution into a continuous flow tubular reactor I, and reacting at 80-110 DEG C for 5-30 minutes to obtain an alkylation reaction solution; feeding the alkylation reaction liquid into a continuous flow tubular reactor II for cooling for 5-10 minutes, wherein the cooling temperature is 20-30 DEG C; and taking out the product, adding the product into a devitrification solution, and performing cooling, devitrifying, stirring, filtering and drying to obtain a product 1,3,5-trimethoxy-2,4,6-trinitrobenzene, wherein the alkylating reagent is a methylation reagent or an ethylation reagent or a propylation reagent. A continuous flow technology is used for inhibiting side reaction, the yield and purity of a target product are improved, and the post-treatment process is greatly simplified. The method can easily control reaction process and is suitable for industrial production.

Preparation method of 1,3,5-trimethoxy-2,4,6-trinitrobenzene

The invention discloses a preparation method of 1,3,5-trimethoxy-2,4,6-trinitrobenzene. The method comprises the following steps: S1, mixing 1, 3, 5-trimethoxybenzene and concentrated sulfuric acid to obtain a first material, and taking a second material of fuming nitric acid; S2, pumping the first material into a pre-cooling module of the micro-channel reactor, and pre-cooling for 0.5-2 minutes; S3, simultaneously pumping the second material and the precooled first material into a mixing module of the microchannel reactor, and uniformly mixing for 0.5-2 minutes; S4, pumping the mixed solution obtained in the step S3 into a reaction module of the micro-channel reactor to react for 0.5-10 minutes; and S5, adding the reacted solution obtained in the step S4 into a collection module of the microchannel reactor, and performing cooling, crystallizing, stirring, filtering and drying to obtain a target product. The reaction time is greatly shortened, the reaction process can be accurately controlled, the synthesis selectivity of the final product is high, byproducts are few, and the yield and purity of the product are obviously improved.

Method for TORTNB etherification synthesis in microreactor

The invention discloses a method for TORTNB etherification synthesis in microreactor. The method includes steps: dissolving a nitrification product TNPG into an organic solvent; simultaneously pumpingTNPG solution and an etherification into a micro mixer,

METHODS OF PRODUCING 1,3,5-TRIAMINO-2,4,6-TRINITROBENZENE

Methods of producing 1,3,5-triamino-2,4,6-trinitrobenzene (TATB), from alkoxy derivatives of phloroglucinol, such as 5-methoxyresorcinol, 3,5-dimethoxyphenol, or 1,3,5-trimethoxybenzene, are disclosed. The alkoxy derivatives may be exposed to and directly nitrated with a reaction mixture comprising a sulfuric acid solution and at least one nitrate salt. The nitrated alkoxy derivative of phloroglucinol may be alkoxylated and, thereafter, aminated to produce the TATB.

Synthesis of trinitroaromatics using alternative mixed acid nitration conditions

Conditions for the mild and efficient nitration of phloroglucinol (1,3,5-trihydroxybenzene), 5-methoxyresorcinol, 3,5-dimethoxyphenol, and 1,3,5-trimethoxybenzene have been developed. Yields of the trinitro derivatives are excellent (～90%) for systems hav

Methods for nitrating compounds

Methods of nitrating compounds, such as phloroglucinol or a methoxy derivative thereof, are disclosed. For example, a reaction mixture may be formed by combining sulfuric acid and at least one nitrate salt. A nitratable aromatic compound, such as phloroglucinol or a methoxy derivative thereof, may then be exposed to the reaction mixture to nitrate the phloroglucinol or methoxy derivative thereof.

Synthesis of trinitrophloroglucinol and triaminotrinitrobenzene (TATB)

A method to convert surplus nitroarene explosives into trinitrophloroglucinol and triaminotrinitrobenzene (TATB) is described. Picric acid is directly aminated to diaminopicric acid, which is converted to trinitrophloroglucinol and triaminotrinitrobenzene.

Crystal and molecular structure of 1,3,5-trimethoxy-2,4,6-trinitrobenzene. Mesomeric effects for out-of-plane twisted substituents

Crystal and molecular structure of 1,3,5-trimethoxy-2,4,6-trinitrobenzene has been determined by X-ray diffraction technique. Crystal data for C9H9N3O9: triclinic, P1, a = 7.507(2) A, b = 9.218(2) A, c = 10.426(