4328-17-0

Basic information

• Product Name: 2,4,6-Trinitro-1,3,5-benzenetriol
• Synonyms: 2,4,6-Trinitro-1,3,5-benzenetriol
• CAS NO: 4328-17-0
• Molecular Formula: C₆H₃N₃O₉
• Molecular Weight: 261.10
• Mol File: 4328-17-0.mol
• Article Data: 14

Chemical Properties

• Melting Point: 167°C
• Boiling Point: 404.36°C (rough estimate)
• Flash Point: 124.3°C
• Appearance: /
• Density: 2.171g/cm³
• Vapor Pressure: 0.0012mmHg at 25°C
• Refractive Index: 1.6910 (estimate)
• PKA: 1.90±0.10(Predicted)
• CAS DataBase Reference: 2,4,6-Trinitro-1,3,5-benzenetriol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-Trinitro-1,3,5-benzenetriol(4328-17-0)
• EPA Substance Registry System: 2,4,6-Trinitro-1,3,5-benzenetriol(4328-17-0)

Safety Data

• Hazardous Substances Data: 4328-17-0(Hazardous Substances Data)

Usage

General Description

2,4,6-Trinitro-1,3,5-benzenetriol, commonly known as trinitrobenzene, is a highly explosive and toxic chemical compound. It is a nitro derivative of phenol and commonly used in the production of explosives, propellants, and dyes. Trinitrobenzene is a yellow crystalline solid that is not soluble in water but is soluble in organic solvents. Due to its explosive nature, trinitrobenzene is highly regulated and its handling requires strict safety measures. Exposure to trinitrobenzene can cause irritation to the skin, eyes, and respiratory tract, as well as systemic toxicity when inhaled or ingested. Overall, trinitrobenzene is a hazardous chemical that requires careful handling and storage to prevent accidents and harm to human health and the environment.

InChI:InChI=1/C6H3N3O9/c10-4-1(7(13)14)5(11)3(9(17)18)6(12)2(4)8(15)16/h10-12H

Upstream product

• 2631-68-7 1,3,5-trichloro-2,4,6-trinitrobenzene 
• 141-52-6 sodium ethanolate 
• 83430-12-0 1,3,5-tribromo-2,4,6-trinitrobenzene 
• 586-11-8 3,5-dinitrophenol 
• 7697-37-2 nitric acid 
• 21985-87-5 2,3,4,5,6-pentanitroaniline 1,2-dichloroethane 
• 134282-24-9 2.4.6.2'.4'.6'-Hexanitro-3.3'-dioxy-azobenzol 
• 859951-43-2 3-chloro-2,4,5,6-tetranitro-phenol 
• 586-10-7 3-methoxy-5-nitroaniline 
• 315-14-0 1,3,5-trifluoro-2-nitrobenzene 
• 18708-70-8 2,4,6-trichloronitrobenzene 
• 200002-30-8 2,4,6-trinitrosobenzene-1,3,5-triol 
• 716306-63-7 2,4,6-trihydroxybenzene-1,3,5-trisulfonic acid 
• 108-73-6 3,5-dihydroxyphenol 

Downstream Products

• 114491-15-5 triaminophloroglucinol hydrogen sulfate 
• 117122-04-0 2,4,6-triamino-phloroglucinol; sulfate 
• 18523-16-5 1,3,5-Trimethoxy-2,4,6-trinitrobenzene 
• 6992-72-9 1,3,5-Triamino-1,3,5-trideoxy-cis-inositol sulfate 
• 19046-89-0 5-Chlor-1,3-dihydroxy-2,4,6-trinitro-benzol 
• 68959-41-1 1,3,5-triethoxy-2,4,6-trinitrobenzene 
• 1235343-60-8 C₆H₃N₃O₉*CH₃N₅ 
• 104704-25-8 C₆H₃N₃O₉*H₃N 

Relevant articles and documents

Converting Unstable Imine-Linked Network into Stable Aromatic Benzoxazole-Linked One via Post-oxidative Cyclization

Efficiently converting unstable linkages into stable linkages is an important objective in the chemistry of covalent organic frameworks (COFs), because it enhances stability and preserves crystallinity. Here, an unstable imine-linked COF was converted int

Three nitro of phloroglucinol synthesis method

The invention discloses a trinitro phloroglucinol synthesizing method which comprises the following steps: mixing phloroglucinol with sulfuric acid to prepare a phloroglucinol solution with the mass fraction of 5 to 50% as a starting material; choosing nitric acid or a mixture of the nitric acid and the sulfuric acid or a mixed solution of nitrate and the sulfuric acid as a nitrating reagent; pumping the starting material and the nitrating reagent into two inlets of a micro-channel reactor through a metering pump in parallel, wherein the molar ratio of the nitric acid or the nitrate in the nitrating reagent to the phloroglucinol in the starting material is controlled as (3.0 to 4.5) to 1 by the metering pump; mixing the starting material and the nitrating reagent in the micro-channel reactor to react, wherein reaction retention time is 1 to 1000 seconds; then outputting from the micro-channel reactor to a collector and reacting continuously for 0.1 to 24 hours. By means of quick heat transfer and mass transfer capacity of the micro-channel reactor, a reaction process can achieve isothermal nitration easily, and intrinsic reaction rate and conversion rate of nitration reaction are improved.

Sequential nitration/hydrogenation protocol for the synthesis of triaminophloroglucinol: Safe generation and use of an explosive intermediate under continuous-flow conditions

A continuous-flow process for the synthesis of triaminophloroglucinol has been developed. The synthetic procedure is based on a sequential nitration/reduction protocol which uses phloroglucinol as an inexpensive substrate. During the initial exothermic nitration step employing a combination of ammonium nitrate and sulfuric acid, the temperature was controlled through the enhanced heat transfer derived from the high surface-to-volume ratio of the utilized capillary tubing. Clogging of the tubing due to precipitation of trinitrophloroglucinol (TNPG) was avoided by immersing the tubular reactor in an ultrasound bath during the process. The nitration mixture was diluted with water and immediately subjected to catalytic hydrogenation of the nitro groups using a commercially available continuous-flow reactor and PtO2 as heterogeneous catalyst, thus avoiding the isolation of the highly unstable and explosive TNPG intermediate.