18584-27-5 Usage
Classification
It is an organic chemical compound and a derivative of acetanilide.
Physical appearance
2-(p-Chlorophenyl)-2-hydroxyacetamide is a white crystalline solid.
Solubility
The compound is sparingly soluble in water but more soluble in organic solvents such as ethanol and ether.
Usage
It is primarily used as an intermediate in the synthesis of various pharmaceuticals, dyes, and other organic compounds.
药理特性
2-(p-Chlorophenyl)-2-hydroxyacetamide exhibits mild analgesic and anti-inflammatory properties.
Limitations
Its use in pharmaceutical applications is limited due to potential toxicity concerns.
Check Digit Verification of cas no
The CAS Registry Mumber 18584-27-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,5,8 and 4 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18584-27:
(7*1)+(6*8)+(5*5)+(4*8)+(3*4)+(2*2)+(1*7)=135
135 % 10 = 5
So 18584-27-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H8ClNO2/c9-6-3-1-5(2-4-6)7(11)8(10)12/h1-4,7,11H,(H2,10,12)
18584-27-5Relevant articles and documents
Bifunctional organometallic catalysts for selective hydration of nitriles to amides
Singh, Kuldeep,Sarbajna, Abir,Bera, Jitendra K.
, p. 853 - 861 (2020/06/26)
In this report, we highlight our recent contributions towards the development of bifunctional catalysts for selective hydration of nitriles to amides.
Condensation of vilsmeier salts, derived from tetraalkylureas, with α-hydroxy amide derivatives: One-pot approach to synthesize 2-dialkylamino-2-oxazolin-4-ones
Liu, Bengen,Su, Dongshan,Wei, Zhonglin,Cao, Jungang,Liang, Dapeng,Lin, Yingjie,Duan, Haifeng
supporting information, p. 249 - 252 (2017/02/10)
A novel and straightforward synthetic protocol was developed to synthesize 2-dialkylamino-2-oxazolin-4-ones from various Vilsmeier salts and α-hydroxy amides derivatives. Notably, thozalinone (3a), as a mild stimulant in tristimania and anorexic, could be synthesized simply and in a high yield using this methodology.
