185854-45-9 Usage
General Description
1,2,3,4-Tetrahydro-2-quinolineacetic acid, also known as tetrahydroquinoline-2-carboxylic acid, is a chemical compound with the molecular formula C11H13NO2. It is a derivative of quinoline and has a tetrahydroquinoline core structure. 1,2,3,4-TETRAHYDRO-2-QUINOLINEACETIC ACID is used in the pharmaceutical industry as an intermediate in the synthesis of various biologically active compounds and drug molecules. It has been studied for its potential pharmacological activities, including its role as an inhibitor of monoamine oxidase (MAO), an enzyme involved in the metabolism of neurotransmitters in the brain. Additionally, 1,2,3,4-Tetrahydro-2-quinolineacetic acid has been investigated for its potential anti-inflammatory, analgesic, and anti-cancer properties.
Check Digit Verification of cas no
The CAS Registry Mumber 185854-45-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,5,8,5 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 185854-45:
(8*1)+(7*8)+(6*5)+(5*8)+(4*5)+(3*4)+(2*4)+(1*5)=179
179 % 10 = 9
So 185854-45-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H13NO2/c13-11(14)7-9-6-5-8-3-1-2-4-10(8)12-9/h1-4,9,12H,5-7H2,(H,13,14)
185854-45-9Relevant articles and documents
Traceless Electrophilic Amination for the Synthesis of Unprotected Cyclic β-Amino Acids
Yu, Jin-Sheng,Espinosa, Miguel,Noda, Hidetoshi,Shibasaki, Masakatsu
supporting information, p. 10530 - 10537 (2019/07/03)
Electrophilic aminations involve an umpolung of a nitrogen atom, providing an alternate, distinctive synthetic strategy. The recent advent of various designed O-substituted hydroxylamines has significantly advanced this research field. An underappreciated
Enzymatic resolution of 2-substituted tetrahydroquinolines. Convenient approaches to tricyclic quinoxalinediones as potent NMDA-glycine antagonists
Katayama, Seiji,Ae, Nobuyuki,Nagata, Ryu
, p. 4295 - 4299 (2007/10/03)
Two approaches leading to the enantiomerically pure tricyclic quinoxalinedione class of NMDA-glycine antagonists using enzymatic resolutions are described. An intermediate, racemic methyl 1,2,3,4- tetrahydroquinoline-2-carboxylate 3, was resolved to (S)-3
